Evidence map›Paper›PMID 40606356›Full record

ArticleQuantitative imaging in medicine and surgery2025

Comparison of ectopic versus normal gray matter via quantitative magnetic resonance imaging: a cross-sectional study.

Dan Luo, Zexiang Deng, Xinru Deng, Xinlan Xiao

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dan Luo *Department of Radiology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Zexiang Deng *Department of Radiology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Xinru DengDepartment of Radiology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Xinlan XiaoDepartment of Radiology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID https://orcid.org/0000-0001-9701-5062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gray matter heterotopia (GMH) involves the abnormal migration of cortical neurons into the white matter and is often associated with epileptic seizures. Although conventional magnetic resonance imaging only provides the anatomical details of GMH, this study investigated the potential differences between GMH and normal gray matter (NGM) using arterial spin labeling (ASL) and magnetic resonance image compilation (MAGiC) quantitative techniques. Methods: Retrospective data collection was conducted on 32 cases of GMH at the Second Affiliated Hospital of Nanchang University between October 2022 and October 2023. Patients underwent T1 brain volume (BRAVO), T2 weight imaging, ASL, and MAGiC sequences. Cerebral blood flow (CBF) values with postlabeling delays of 1.5 s and 2.5 s in ASL, along with T1, T2, and proton density values in MAGiC sequences, were measured and normalized against those of normal white matter. Paired-sample Results: The average CBF values of GMH with dual postlabeling delays (31.96 mL/100 g/min and 35.13 mL/100 g/min) were both significantly lower than those of NGM (52.69 mL/100 g/min and 56.93 mL/100 g/min) (P<0.001). After normalization with contralateral white matter CBF values, the difference remained significant (P<0.001). The differences in CBF values between GMH and NGM were not associated with the postlabeling delay (P=0.500). However, there were differences in T1 values between NGM and GMH before and after the normalization of MAGiC sequences (P<0.001), but no significant differences were observed in the T2 or proton density values before and after normalization (P>0.05). Conclusions: NGM and GMH demonstrate quantitative differences in the ASL and MAGiC sequences.

Indexed as

arterial spin labeling (ASL)Gray matter heterotopia (GMH)magnetic resonance image compilation (MAGiC)

Identifiers

PMID40606356
PMCPMC12209660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.