ArticleQuantitative imaging in medicine and surgery2025
Performance comparison of dual-layer detector CT parameters from different blood vessels in the detection of anemia.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Anemia negatively affects an individual's overall prognosis and quality of life, and thus represents a significant health burden. Dual-layer computed tomography (DLCT) detector imaging enables substance differentiation. This study aimed to compare the performance of DLCT parameters for different blood vessels in detecting anemia. Methods: DLCT parameter values [i.e., the computed tomography (CT) value, effective atomic number, and electron density] were retrospectively derived from the aortic arch, pulmonary artery, and portal vein of 240 patients. Differences in DLCT parameters between the anemia and normal groups were analyzed. Pearson correlation analysis and logistic regression models were employed to examine the relationships between the DLCT parameters and hemoglobin concentration. The diagnostic performance of DLCT parameters for anemia among different blood vessels was evaluated by receiver operating characteristic (ROC) analysis. Results: The anemia group (n=101) had significantly lower hemoglobin concentration than the normal group (n=139) (107.96±13.95 Conclusions: DLCT may assist in the detection of anemia. The DLCT parameters of the aortic arch demonstrated higher performance than those of the pulmonary artery and portal vein. Additionally, integrating different DLCT parameters (i.e., the CT value and electron density) of multiple vessels may improve diagnostic performance.
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