ArticleFrontiers in microbiology2025
Clinical efficacy of probiotics in improving intestinal mucosal permeability for functional dyspepsia patients with anxiety.
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The aim of this study was to investigate whether probiotics are effective in improving symptoms of functional dyspepsia (FD) accompanied by anxiety. Methods: There were 116 patients with FD accompanied by anxiety and 114 patients without anxiety. Each group was randomly divided into an intervention group and a control group. The intervention group received probiotics in addition to conventional acid suppression and gastric protection, as well as prokinetic treatments. The control group received conventional treatment plus a placebo. Results: Before treatment, significant differences were observed in IL-1, IL-6, TNF- Conclusion: The intervention significantly improved the symptoms and anxiety scores of patients with FD and anxiety, and the changes in intestinal mucosal permeability indexes were closely related to symptom relief and anxiety improvement, Probiotic interventions may be an effective means of improving symptoms in patients with FD. Clinical trial registration: identifier ChiCTR2300077847 https://www.chictr.org.cn/.
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