Evidence map›Paper›PMID 40606122›Full record

SynthesisFrontiers in public health2025

Effect of exercise intervention on quality of life and exercise capacity in patients with atrial fibrillation: a systematic review and network meta-analysis.

Yaya Xi, Yinxue Zhang, Leyao Han, Meishan Zhang, Yunyun Liu, Jingying Xiong, Yingqiao Wang, Weiping Li, Feng Bai, Minmin Cai and 2 more

Abstract readNetwork Meta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yaya Xi *School of Nursing, Lanzhou University, Lanzhou, China.
Yinxue Zhang *Department of Cardiovascular Medicine, Lanzhou University Second Hospital, Lanzhou, China.
Leyao HanSchool of Nursing, Lanzhou University, Lanzhou, China.
Meishan ZhangSchool of Nursing, Lanzhou University, Lanzhou, China.
Yunyun LiuSchool of Nursing, Lanzhou University, Lanzhou, China.
Jingying XiongSchool of Nursing, Lanzhou University, Lanzhou, China.
Yingqiao WangSchool of Nursing, Lanzhou University, Lanzhou, China.
Weiping LiSchool of Nursing, Lanzhou University, Lanzhou, China.
Feng BaiDepartment of Cardiovascular Medicine, Lanzhou University Second Hospital, Lanzhou, China.
Minmin CaiDepartment of Cardiovascular Medicine, Lanzhou University Second Hospital, Lanzhou, China.
Xinman DouSchool of Nursing, Lanzhou University, Lanzhou, China.
Xinglei WangSchool of Nursing, Lanzhou University, Lanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF), the most prevalent cardiac arrhythmia, can significantly increase stroke risk, heart failure, and reduce quality of life. Despite growing evidence on the benefits of exercise for AF patients, data heterogeneity and the lack of comparative studies on different exercise modalities limit the accuracy of clinical recommendations. Objective: To compare the effects of different exercise regimens on AF and determine the most effective type of exercise for the treatment of AF. Methods: We systematically searched PubMed/Medline, Embase, the Cochrane Library, and Web of Science for randomized controlled trials of exercise interventions in patients with AF aged 18 years and older. The Cochrane Collaboration Risk of Bias tool (RoB 2) was utilized to assess the risk of bias. We used R software to perform a network meta-analysis. The protocol has been registered with PROSPERO (Number CRD42024628296). Results: A total of 1,477 participants from 16 randomized controlled trials were included in this network meta-analysis. The results indicated that mind-body exercise (MB) was the most effective in improving general health [mean difference (MD) = 12.26, 95% credible intervals (95% Crl): 6.47 to 18.04, surface under the cumulative ranking curve (SUCRA) = 76.31%] and 6-min walk test (MD = 104.80, 95% Crl: 44.25 to 165.10, SUCRA = 99.60%). Additionally, aerobic exercise (AE) was the most effective in increasing vitality (MD = 7.73, 95% Crl: 6.40 to 9.07, SUCRA = 88.07%). Conclusion: This network meta-analysis found that MB had superior effects on general health and exercise capacity. AE significantly improved vitality, social functioning, and mental health, with particular benefits in improving vitality. Systematic review registration: https://www.crd.york.ac.uk/prospero, identifier (CRD42024628296).

Indexed as

Atrial FibrillationExerciseExercise TherapyExercise ToleranceQuality of LifeHumansMaleRandomized Controlled Trials as Topicatrial fibrillationexerciseexercise capacitynetwork meta-analysisquality of life

Identifiers

PMID40606122
PMCPMC12213351

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.