ArticleFrontiers in public health2025
HIV-related stressors and psychological functioning among adolescents living with perinatal HIV in KwaZulu-Natal, South Africa.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Correlates of Viral Suppression in Adolescents With HIV Taking Antiretroviral Therapy in Mozambique: Results of a Multicenter Cross-Sectional Survey.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026Article
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Abstract
Introduction: Adolescents with perinatally acquired HIV (APHs) in sub-Saharan Africa (SSA) face significant psychological challenges due to HIV-related stressors such as stigma and the burden of chronic illness, which can negatively impact mental health and antiretroviral therapy (ART) adherence. Mental health issues, including depression and anxiety, are common among APHs and often compounded by poverty, orphanhood, and stigma affecting both APHs and their caregivers. This study examines associations between HIV-related stressors (stigma experienced by APHs and their caregivers and the caregiver-perceived burden of the child's illness) and psychological functioning (depressive symptoms, anxiety, and self-esteem) among APHs in South Africa. Methods: This cross-sectional study analyzed baseline data from the VUKA Family Program, an intervention in KwaZulu-Natal, South Africa (2014-2019). The sample included 315 APHs (aged 9-15) and their caregivers. Descriptive statistics assessed psychological functioning and HIV-related stressors. Multivariate regression analyses examined associations between APH-perceived stigma, caregiver-experienced stigma, caregiver-reported burden of the child's illness, and psychological functioning outcomes. Results: Most APHs ( Discussion: Findings highlight the critical role of HIV-related stigma in shaping APH mental health. Addressing stigma among APHs and caregivers through targeted interventions may improve psychological outcomes. Future research should explore self-esteem as a protective factor and validate depression scales for APHs in SSA.
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