Evidence map›Paper›PMID 40606041›Full record

ArticlePulmonary circulation2025

Outpatient Intravenous Dobutamine as Right Ventricular Support During Inhaled Prostacyclin Uptitration in Severe PH-ILD.

A Kumar, Siddharth V Ramanan, Brett Carollo, Kristen Swanson, Raj Parikh

Abstract readLetter
In one paragraph

Article in Pulmonary circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A KumarDepartment of Internal Medicine University of Connecticut School of Medicine Farmington Connecticut USA.ORCID https://orcid.org/0000-0002-8327-2559
Siddharth V RamananDepartment of Internal Medicine University of Connecticut School of Medicine Farmington Connecticut USA.ORCID https://orcid.org/0000-0002-1822-1130
Brett CarolloDivision of Pulmonary, Critical Care and Sleep Hartford Hospital Hartford Connecticut USA.
Kristen SwansonDivision of Pulmonary, Critical Care and Sleep Hartford Hospital Hartford Connecticut USA.
Raj ParikhDivision of Pulmonary, Critical Care and Sleep Hartford Hospital Hartford Connecticut USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PH-ILD carries a poor prognosis, particularly with PVR > 5 WU. The INCREASE trial demonstrated the successful use of inhaled treprostinil, but slow uptitration delays the effects. Our study suggests outpatient IV dobutamine as interim support, improving contractility and reducing PVR during uptitration.

Indexed as

dobutamineinterstitial lung diseaseprostacyclinpulmonary arterial hypertensionright ventricular failure

Identifiers

PMID40606041
PMCPMC12215808

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.