Evidence map›Paper›PMID 40606016›Full record

ArticleEuropean heart journal. Case reports2025

Cardiac lymphoma requiring urgent heart transplant due to ventricular tachycardia storm: a case report.

Julián Lugo-Peña, Héctor M Medina, Juan P Umaña, María Daniela Valderrama-Achury, Adriana Torres

Abstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julián Lugo-PeñaDepartment of Clinical Cardiology, Fundación Cardioinfantil-Instituto de Cardiología, Calle 163A # 13B-60, Bogotá 110311, Colombia.ORCID https://orcid.org/0000-0002-5867-2876
Héctor M MedinaCardiac Imaging, Texas Heart Institute, 6770 Bertner Avenue, Houston, TX 77030, USA.
Juan P UmañaChair, Division of Thoracic & Cardiovascular Surgery, Cleveland Clinic, 3100 Weston Road, Weston, FL 33331, USA.
María Daniela Valderrama-AchuryResearch Institute of the McGill University Health Centre, 845 Sherbrooke Stw, Montreal, Quebec, Canada, H3A 0G4.
Adriana TorresHeart Failure Unit Los Cobos Medical Center, Avenida 9 " 131-40, Bogotá 111321, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Primary cardiac lymphoma (PCL) involves the heart almost exclusively although it can extend to surrounding structures including the pericardium. Most PCLs in adults are of B-cell origin and their signs and symptoms are generally non-specific and depend on their location and size. In general, cancer patients usually have a slim chance of receiving heart transplantation (OHT), although it's not an absolute contraindication depending on the decision of the multidisciplinary team and the experience of each institution. Case Summary: A 48-year-old man, with an ultimate diagnosis of primary cardiac follicular B-cell lymphoma presented to our hospital mimicking hypertrophic cardiomyopathy. He initially presented with worsening heart failure and ventricular tachycardia storm (VT-S) that required urgent cardiac OHT. The final pathological analysis of the explanted heart revealed the presence of a PCL without extra-cardiac extension. In addition to initial immunosuppression with mycophenolate mophethyl, corticosteroids, and tacrolimus, he was switched to Everolimus and dose reduction of Tacrolimus. Rituximab + Bendamustine was initiated to reduce the risk of cardiotoxicity and myelotoxicity associated to R-CHOP. The follow-up body PET-CT, Discussion: After 5.5 years of follow-up, the patient remains asymptomatic, with normal graft function, in NYHA FC I, and without oncological relapses despite receiving a modified chemotherapy regimen. Selected patients with a PCL can be managed with OHT and a modified chemotherapy regimen. They could also be followed up using a non-invasive approach to monitor rejection.

Indexed as

Cardiac lymphomaCardiac transplantationCase reportChemotherapyLong-term follow-upVentricular tachycardia

Identifiers

PMID40606016
PMCPMC12210231

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.