Evidence map›Paper›PMID 40605687›Full record

Observational studyESC heart failure2025

Home-operated ultrasound exam for detection of worsening heart failure (HOUSE-HF).

Stuart B Prenner, Kevin Dougherty, Frances S Shofer, Lee R Goldberg, Nova Panebianco

Abstract readObservational Study
In one paragraph

Observational study in ESC heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stuart B PrennerDivision of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-6996-3804
Kevin DoughertyDrexel University Thomas R Kline School of Law, Philadelphia, Pennsylvania, USA.
Frances S ShoferDivision of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lee R GoldbergDivision of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Nova PanebiancoDivision of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Funding

Butterfly
6 · The paper itself

Abstract

aimsAcute decompensated heart failure (ADHF) is associated with a high degree of morbidity and mortality. Dynamic lung ultrasound artefact called B-lines can be obtained at the bedside and directly correlate with pulmonary vascular congestion. Obtaining patient-performed lung ultrasound images in the outpatient setting is novel. We assessed the feasibility of patients recently hospitalized for ADHF to self-perform a limited lung ultrasound using a handheld ultrasound probe and upload the images to a secure cloud for physician interpretation.

methodsThis was a prospective observational convenience sample. Patients were enrolled from an urban academic tertiary care centre and were eligible if they had chronic left-sided heart failure regardless of ejection fraction. While hospitalized, patients were educated for 20 min on a six-lung-zone image protocol, how to use the cloud archival system and given a handheld ultrasound transducer and smart tablet. A brief instructional video was also available to patients on the smart tablet throughout the study (https://www.dropbox.com/scl/fi/bii7ovdcv21ps7yxyqsy1/120-21080-00-Rev-01-BNI-041-UPENN-IN-APP-TRAINING-VIDEO.mp4?rlkey=f5vu55xbnugdoz6jzyb8lv872&st=56es4qif&dl=0). Patients were asked to upload images three times weekly, for 3 weeks, for a total of nine studies. All images were reviewed and a B-line score was calculated for each lung zone, and a total B-line score for the entire exam. Additionally, patients completed a survey to assess the patient-centred experience.

resultsA total of 15 patients were enrolled, all of whom completed seven or more studies (10 patients completed all 9). Median patient age was 63 years (range: 28 -86 years), the majority were male (73%), white (60%) and average body mass index was 33 kg/m

conclusionsThis pilot study demonstrates that patients with hospitalized ADHF can be taught to use a handheld portable ultrasound device and obtain and upload high quality lung ultrasound images. Compliance with the study protocol and ability to obtain some images were excellent. Further studies are needed to determine if patient-performed lung ultrasound can help detect and manage acute worsening HF in this patient population.

Indexed as

Heart FailureLungStroke VolumeAgedAged, 80 and overDisease ProgressionFeasibility StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesSelf CareUltrasonographyADHFB‐linespatient‐centredPOCUSultrasound

Identifiers

PMID40605687
PMCPMC12450772

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.