Evidence map›Paper›PMID 40605643›Full record

ArticleAlcohol, clinical & experimental research2025

Examining the relationship between cannabis use and drinking levels on co-use days.

Holly K Boyle, Alexander W Sokolovsky, Rachel L Gunn, Jordan A Gette, Helene R White, Kristina M Jackson

Abstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Holly K BoyleDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.
Alexander W SokolovskyCenter for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA.ORCID 0000-0003-3545-5745
Rachel L GunnCenter for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA.ORCID 0000-0001-5244-1105
Jordan A GetteDepartment of Psychiatry and Human Behavior, University of Kansas Medical Center, Kansas City, Kansas, USA.
Helene R WhiteCenter of Alcohol and Substance Use Studies, Rutgers University, Piscataway, New Jersey, USA.ORCID 0000-0002-4045-6585
Kristina M JacksonRutgers Addiction Research Center, Brain Health Institute, Rutgers University, Piscataway, New Jersey, USA.

Funding

SUBSTANCE ABUSEK12DA000167 · NIDA · YALE UNIVERSITY · PI STEPHANIE S O'MALLEY, Marc N Potenza · 1991 to 2026
$17.7M
ALCOHOL INTERVENTION/TREATMENT OUTCOME RESEARCH TRAININGT32AA007459 · NIAAA · BROWN UNIVERSITY · PI ROBERT MIRANDA, PETER M. MONTI · 1986 to 2026
$13.3M
Motivational and Contextual Influences on Patterns of Simultaneous Alcohol and Marijuana Use: A Daily Assessment StudyR01DA040880 · NIDA · BROWN UNIVERSITY · PI JACKSON, KRISTINA MELIA, WHITE, HELENE R. · 2016 to 2018
$2.0M
Dual Use of ENDS and Combustible Cigarettes: Shared, Distinct, and Cross-Conditioned ProcessesK08DA048137 · NIDA · BROWN UNIVERSITY · PI SOKOLOVSKY, ALEXANDER WILLIAM · 2020 to 2024
$976k
NIAAA NIH HHS T32 AA007459NIDA NIH HHS K08 DA048137NIDA NIH HHS K12 DA000167NIDA NIH HHS R01 DA040880
6 · The paper itself

Abstract

backgroundCo-use of alcohol and cannabis among young adults is often associated with more alcohol consumption than alcohol-only use, yet little work has examined cannabis use specifically during heavy drinking. Much of the work examining heavy drinking has focused on heavy episodic drinking (HED, 4+/5+ drinks/occasion for females/males); however, young adults report drinking levels that far exceed this, frequently reporting high-intensity drinking (HID; 8+/10+ drinks/occasion for females/males), double the HED threshold, which confers greater risk of acute negative consequences. This study examined whether day-level co-use (vs. alcohol-only use) was associated with greater odds of heavier drinking levels: HID vs. HED vs. moderate drinking (1-3/1-4 drinks/occasion for females/males). We explored whether within-person variations in cannabis use characteristics (frequency, form, and quantity) differentiated moderate drinking, HED, and HID on co-use days.

methodsYoung adults who reported simultaneous alcohol and cannabis use (N = 318) from three US universities completed five repeated daily surveys for 54 days reporting number of drinks and number of cannabis uses (i.e., frequency/events), forms, and quantity.

resultsParticipants reported increased likelihood of HID and HED versus moderate drinking on co-use versus alcohol-only days. HID versus HED did not differ between co-use and alcohol-only days. On co-use days, heavier drinking was more likely on days with more cannabis use. The form of cannabis used and the use of multiple versus single forms of cannabis were not associated with drinking level. Yet, HID was more likely than HED and moderate drinking when more grams of flower were used and HID was also more likely than moderate drinking when more hits of concentrates were used.

conclusionsFindings show heavy drinking (HID, HED) was more likely than moderate drinking on co-use days and cannabis use characteristics may influence drinking levels. Co-use interventions may benefit from a focus on heavy drinking and cannabis use characteristics.

Indexed as

Alcohol DrinkingMarijuana UseAdolescentAdultAlcohol Drinking in CollegeFemaleHumansMaleStudentsSurveys and QuestionnairesUniversitiesYoung Adultcannabis useco‐use of alcohol and cannabisheavy episodic drinkinghigh‐intensity drinkingyoung adults

Identifiers

PMID40605643
PMCPMC12344779

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.