Evidence map›Paper›PMID 40605567›Full record

ReviewNeurourology and urodynamics2026

Interstitial Cystitis/Bladder Pain Syndrome in Men.

Madeline Snipes, Wyatt Whitman, Michel Pontari, Jennifer Anger, Michael Samarinas, Rajesh Taneja

Abstract readReview
In one paragraph

Review in Neurourology and urodynamics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Madeline SnipesDepartment of Urology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID https://orcid.org/0000-0001-5209-7631
Wyatt WhitmanDepartment of Urology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Michel PontariLewis Katz School of Medicine at Temple University/Fox Chase Temple Urological Institute, Philadelphia, Pennsylvania, USA.
Jennifer AngerDepartment of Urology, University of California at San Diego, San Diego, California, USA.ORCID https://orcid.org/0000-0002-7688-4688
Michael SamarinasDepartment of Urology, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID https://orcid.org/0000-0001-9424-795X
Rajesh TanejaUrology Andrology, and Robotic Surgery, Indraprastha Apollo Hospitals, New Delhi, India.ORCID https://orcid.org/0000-0002-1726-9263

Funding

The production of this manuscript was not supported by any outside funding.
6 · The paper itself

Abstract

aimsIn April 2025, the Wake Forest Institute for Regenerative Medicine hosted a Global Consensus meeting on interstitial cystitis/bladder pain syndrome (IC/BPS) in Winston-Salem, NC. The goal of this meeting was to establish attainable targets in phenotyping, diagnosis, and biomarkers for IC/BPS. Our subcommittee focused on developing a consensus document addressing IC/BPS in men.

methodsNarrative review.

resultsWithin this document, we discuss prevalence, clinical characteristics, evaluation/investigation, and treatment of IC/BPS in men. The is limited literature specifically addressing IC/BPS within the male population, as IC/BPS has traditionally been considered a disease of women. Thus, prevalence data varies widely. Diagnosis of IC/BPS in men is fraught with difficulty, as there is much overlap with other chronic pelvic pain syndrome, specifically chronic prostatitis. Key clinical features specific to IC/BPS are pain with bladder filling and relief with voiding. Painful ejaculation may be indicative of pelvic floor dysfunction. Physical exam, including extensive pelvic exam with analysis of pelvic floor tenderness, is critical in correct diagnosis. Ultrasound +/- urodynamics may be used to rule out obstructive disease, and urinalysis +/- culture must be used to rule out infection. There are no treatments specific to men with IC/BPS.

conclusionsWe have described the prevalence, clinical characteristics, evaluation, and treatment of IC/BPS in men. There is a significant need for more sex-specific research of IC/BPS with consideration for hormonal and anatomical factors that may differentiate the disease in men. CLINICAL

trial registrationNo new data were generated for this manuscript; no clinical trial was conducted.

Indexed as

Cystitis, InterstitialPelvic PainHumansMalePrevalencebladder‐capacitychronic pelvic pain syndromechronic prostatitisdiagnosisHunner lesiontreatment

Identifiers

PMID40605567
PMCPMC12748021

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.