Evidence map›Paper›PMID 40605509›Full record

ArticleAnnals of medicine2025

Global, regional, and national burden of hearing loss from 1990 to 2021: findings from the 2021 global burden of disease study.

Ying Shen, Tianjiao Zhou, Wentao Zou, Jiaxiong Zhang, Shuwen Yan, Haibo Ye, Weijun Huang

Abstract read
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The Gut-Ear Axis: From Dysbiosis to Auditory and Vestibular Disorders.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Recent Progress in Mechanism-Based Therapies forInternational journal of molecular sciences · 2026
    Review
  8. Hearing Protection Among Workers Exposed to Occupational Noise in the South African Aluminium Industry.International journal of environmental research and public health · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying ShenDepartment of Otolaryngology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.ORCID 0000-0001-7729-2951
Tianjiao ZhouDepartment of Otorhinolaryngology Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wentao ZouDepartment of Otolaryngology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Jiaxiong ZhangDepartment of Otolaryngology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Shuwen YanDepartment of Clinical Medicine, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Haibo YeDepartment of Otolaryngology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Weijun HuangDepartment of Otorhinolaryngology Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0001-7256-812X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHearing loss is a global health issue affecting millions and imposing a significant burden. This study aimed to retrospectively and predictively assess the prevalence and years lived with disability (YLDs) due to hearing loss, stratified by sociodemographic index (SDI), age, and sex.

methodsData from the 2021 Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) were used to analyze the prevalence and YLD burden of hearing loss across different subgroups. Age-standardized prevalence rates (ASPR), age-standardized YLD rates (ASYR), and estimated annual percentage changes (EAPCs) were calculated to assess trends.

resultsIn 2021, over 1.5 billion individuals had hearing loss, resulting in significant disability burden. EAPCs for ASPR and ASYR from 1990 to 2021 were 0.16 (95% confidence intervals [CI]: 0.15-0.17) and 0.17 (0.16-0.18) respectively. Regions with middle SDI had the highest prevalence, ASPR, YLDs, and ASYR, while high SDI regions had the lowest. ASYR and ASPR were negatively correlated with SDI across regions in most regions. Males had significantly higher ASPR and ASYR than females. ASPR and ASYR increased with age. Projections from 2022 to 2050 indicated a continued rise in ASPR, with a slight decline in ASYR.

conclusionsHearing loss burden increased from 1990 to 2021, with notable differences across regions, genders, and age groups. High SDI areas had the lowest burden, while middle SDI regions experienced the most severe hearing loss. Low SDI areas had a higher disability ratio relative to prevalence. Males and older adults bore a disproportionately high burden of hearing loss.

Indexed as

Global Burden of DiseaseHearing LossAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCost of IllnessDisability-Adjusted Life YearsFemaleGlobal HealthHumansInfantMaleMiddle Ageddisabilitydisease trendsGlobal burdenhearing lossprevalencesociodemographic index

Identifiers

PMID40605509
PMCPMC12231259

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.