Evidence map›Paper›PMID 40605177›Full record

ArticleRNA biology2025

Novel non-coding FOXP3 transcript isoform associated to potential transcriptional interference in human regulatory T cells.

Marcos Cases, Niclas Ritter, Hector Rincon-Arevalo, Sandy Kroh, Aysegül Adam, Marieluise Kirchner, Hanieh Moradian, Manfred Gossen, Maria Dzamukova, Artür Manukyan and 6 more

Abstract read
In one paragraph

Article in RNA biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. International journal of molecular sciences · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Marcos CasesFlow Cytometry Core Facility, Deutsches Rheuma-Forschungszentrum Berlin, A Leibniz Institute (DRFZ), Berlin, Germany.ORCID 0009-0003-9689-9005
Niclas RitterInstitute of Virology, Hannover Medical School, Hannover, Germany.
Hector Rincon-ArevaloDepartment of Medicine, Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Sandy KrohDivision of Rheumatology and Clinical Immunology, Charité, Universitätsmedizin Berlin, Berlin, Germany.
Aysegül AdamImmune Dynamics, Deutsches Rheuma-Forschungszentrum (DRFZ), A Leibniz Institute, Berlin, Germany.
Marieluise KirchnerCore Unit Proteomics, Berlin Institute of Health at Charité- Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine (MDC), Berlin, Germany.
Hanieh MoradianInstitute of Active Polymers, Helmholtz-Zentrum Hereon, Teltow, Germany.
Manfred GossenInstitute of Active Polymers, Helmholtz-Zentrum Hereon, Teltow, Germany.
Maria DzamukovaDeutsches Rheuma-Forschungszentrum Berlin, Ein Institut der Leibniz-Gemeinschaft, Berlin, Germany.
Artür ManukyanBerlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Markus LandthalerBerlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Christopher KresslerBerlin Institute of Health (BIH) at Charité Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), Immuno-Epigenetics Group, Berlin, Germany.
Anja E HauserDivision of Rheumatology and Clinical Immunology, Charité, Universitätsmedizin Berlin, Berlin, Germany.
Daniel P DepledgeInstitute of Virology, Hannover Medical School, Hannover, Germany.
Julia K PolanskyBerlin Institute of Health (BIH) at Charité Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT), Immuno-Epigenetics Group, Berlin, Germany.
Hyun-Dong ChangSchwiete laboratory for microbiota and inflammation, DRFZ, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD4+ regulatory T cells (T

Indexed as

Forkhead Transcription FactorsT-Lymphocytes, RegulatoryTranscription, Genetic5' Untranslated RegionsGene Expression RegulationHumansPromoter Regions, GeneticProtein IsoformsRNA, Messenger5' Untranslated RegionsForkhead Transcription FactorsFOXP3 protein, humanProtein IsoformsRNA, Messengeralternative promoterFOXP3transcriptional interferencetranscript isoformTREG

Identifiers

PMID40605177
PMCPMC12233831

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.