Evidence map›Paper›PMID 40605026›Full record

ArticleBMC chemistry2025

Synthesis of novel trans-2,3-dihydrofuran-pyrazole conjugates through molecular hybridization: molecular docking insights and evaluation of anti-inflammatory and anti-malarial activities.

Ginna Kumari, Priyanka Rani, Sudeep Dhillon, Mamta Chahal, Binesh Kumar, Jai Devi, Deepak Kumar Aneja, Mayank Kinger

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ginna KumariDepartment of Chemistry, Chaudhary Bansi Lal University, Bhiwani, 127031, Haryana, India.
Priyanka RaniDepartment of Chemistry, Chaudhary Bansi Lal University, Bhiwani, 127031, Haryana, India.
Sudeep DhillonDepartment of Chemistry, Chaudhary Bansi Lal University, Bhiwani, 127031, Haryana, India.
Mamta ChahalDepartment of Chemistry, Chaudhary Bansi Lal University, Bhiwani, 127031, Haryana, India.
Binesh KumarDepartment of Chemistry, Guru Jambheshwar University of Science and Technology, Hisar, 125001, Haryana, India.
Jai DeviDepartment of Chemistry, Guru Jambheshwar University of Science and Technology, Hisar, 125001, Haryana, India.
Deepak Kumar AnejaDepartment of Chemistry, Chaudhary Bansi Lal University, Bhiwani, 127031, Haryana, India.
Mayank KingerDepartment of Chemistry, Chaudhary Bansi Lal University, Bhiwani, 127031, Haryana, India. drmayankkinger@cblu.ac.in.ORCID http://orcid.org/0000-0002-4269-0834

Funding

Council of Scientific and Industrial Research (CSIR), New Delhi, India 09/457(7549)/2020-EMRUniversity Grant Commission, New Delhi, India 7977678250University Grant Commission, New Delhi, India 88/(CSIR-UGC NET JUNE 2019
6 · The paper itself

Abstract

A series of some new trans 2,3-dihydrofuran-linked pyrazole hybrids were synthesized from a convenient one-pot methodology. This procedure employs a sequential one-pot, two-step tandem reaction starting from pyridine, formylpyrazole, dimedone, and phenacyl bromide, with triethylamine serving as the base and proceeds efficiently in acetonitrile. The recently synthesized compounds were characterized through

Indexed as

Anti-malarial activityDihydrofuranInflammationMolecular dockingPyrazole

Identifiers

PMID40605026
PMCPMC12224374

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.