Evidence map›Paper›PMID 40605008›Full record

ArticleBMC chemistry2025

Efficient synthesis of N-(ethylcarbamothioyl)-1-naphthamide: X-ray structure, Hirshfeld surface analysis, DFTs, and molecular modelling investigations as selective inhibitor of alkaline phosphatase.

Pervaiz Ali Channar, Mohammad Y Alshahrani, Aamer Saeed, Syeda Abida Ejaz, Hafiz Muhammad Attaullah, Sajid Ali Channar, Sher Qadir, Qamar Abbas, Ulrich Flörke, Tuncer Hökelek

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Article in BMC chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pervaiz Ali ChannarDepartment of Basic sciences and Humanities, Faculty of Information Sciences and Humanities, Dawood University of Engineering and Technology Karachi, Karachi, 74800, Pakistan. pervaiz.ali@duet.edu.pk.
Mohammad Y AlshahraniDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, P.O. Box 61413, Abha, 9088, Saudi Arabia.
Aamer SaeedDepartment of Chemistry, Quaid-I-Azam University, Islamabad, 45320, Pakistan. aamersaeed@yahoo.com.
Syeda Abida EjazDepartment of Pharmaceutical Chemistry, Faculty of pharmacy, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan. abida.ejaz@iub.edu.pk.
Hafiz Muhammad AttaullahDepartment of Pharmaceutical Chemistry, Faculty of pharmacy, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Sajid Ali ChannarDr. M. A. Kazi Institute of Chemistry, University of Sindh, Jamshoro, Pakistan.
Sher QadirDepartment of Chemistry, Allama Iqbal Open University, Islamabad, 44000, Pakistan.
Qamar AbbasDepartment of Biology, College of Science, University of Bahrain, Sakhir, Kingdom of Bahrain.
Ulrich FlörkeDepartment of Chemistry, Faculty of Natural Sciences, University of Paderborn, Warburger Straße 100, 33098, Paderborn, Germany.
Tuncer HökelekDepartment of Physics, Hacettepe University, Beytepe-Ankara, 06800, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naphthyl Thiourea based derivative N-(ethylcaramothbioyl)-1-naphthamide (NA-MT) was synthesized by freshly prepared 1-naphthoyl isothiocyanate with ethyl amine to afford the products (NA-MT) high purity and characterized via spectroscopic techniques including FTIR,

Indexed as

Alkaline phosphataseHirshfeld surface analysisMolecular dockingMolecular dynamic simulationsNaphthoyl thioureas

Identifiers

PMID40605008
PMCPMC12225141

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.