Evidence map›Paper›PMID 40604998›Full record

ArticleBMC veterinary research2025

Plague and tularemia surveillance in hormozgan province, Southern Iran.

Hossein Ahangari Cohan, Saber Esmaeili, Ahmad Mahmoudi, Ahmad Ghasemi, Amir Hesam Nemati, Mohammad Mehdi Gooya, Abdoljabbar Zakeri, Ehsan Mostafavi

Abstract read
In one paragraph

Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Molecular Tracing and Comparative Genomics Analysis ofPathogens (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hossein Ahangari CohanNational Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Kabudar Ahang, Iran.
Saber EsmaeiliNational Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Kabudar Ahang, Iran.
Ahmad MahmoudiDepartment of Biology, Faculty of Science, Urmia University, Urmia, Iran.
Ahmad GhasemiNational Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Kabudar Ahang, Iran.
Amir Hesam NematiNational Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Kabudar Ahang, Iran.
Mohammad Mehdi GooyaCenter of Disease Control (CDC), Ministry of Health, Tehran, Iran.
Abdoljabbar ZakeriSocial Determinants in Health Promotion Research Center, Research Institute for Health, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Ehsan MostafaviNational Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Kabudar Ahang, Iran. mostafaviehsan@gmail.com.

Funding

Pasteur Institute of Iran 1744
6 · The paper itself

Abstract

backgroundPlague and tularemia are endemic rodent-borne zoonoses in Iran. This study investigated their presence of these diseases in wildlife populations in southern Iran. Sheepdogs were also surveyed as sentinel animals to provide early warning of potential outbreaks.

methodsIn August 2018, sampling involved the capturing rodents and collecting blood from wild carnivores and sheepdogs. Rodent spleen tissues and ectoparasites were analyzed using real-time PCR to detect Yersinia pestis (targeting the yihN, pla, and caf1 genes) and Francisella tularensis (targeting the ISFtu2 and fopA genes). All tissue samples underwent bacterial isolation. Additionally, rodents, wild carnivores, and sheepdogs were screened for specific antibodies to assess pathogen exposure.

resultsA total of 65 rodents were captured, primarily Rattus rattus (35.38%), Tatera indica (29.23%), and Acomys dimidiatus (20%). Serological surveys included 35 domestic sheepdogs (Canis lupus familiaris), 4 jackals (Canis aureus), and 3 Indian grey mongooses (Urva edwardsi). Thirty fleas, all of the genus Xenopsylla, were collected as ectoparasites. All samples tested negative for tularemia via agglutination assay. No wild mammals showed seropositivity, but plague-specific antibodies were detected in 4 sheepdogs (11.42%). Molecular tests and bacterial cultures for both plague and tularemia were negative.

conclusionThe presence of plague-specific antibodies in sheepdogs suggest possible plague circulation in southern Iran, indicating a potential risk of human exposure.

Indexed as

PlagueTularemiaAnimalsAnimals, WildAntibodies, BacterialCarnivoraFrancisella tularensisIranRodent DiseasesRodentiaSiphonapteraYersinia pestisAntibodies, BacterialFrancisella tularensisIranRodentsSheepdogsYersinia pestis

Identifiers

PMID40604998
PMCPMC12220604

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.