Evidence map›Paper›PMID 40604905›Full record

ArticleDiabetology & metabolic syndrome2025

The association between alcohol and metabolic syndrome: a systematic review and meta-analysis.

Maedeh Arshadi, Elahe Mansouri Yekta, Maryam Kazemi, Elham Khaledi, Zahra Beygi, Hosein Azizi, Farzad Khodamoradi

Abstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maedeh ArshadiDepartment of Epidemiology and Biostatistics, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Elahe Mansouri YektaDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Maryam KazemiDepartment of Epidemiology and Biostatistics, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Elham KhalediDepartment of Epidemiology and Biostatistics, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Zahra BeygiDepartment of Epidemiology and Biostatistics, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Hosein AziziWomen's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Farzad KhodamoradiDepartment of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. f_khodamoradi@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome studies have shown that there is a relationship between alcohol and metabolic syndrome, and some studies have not found an association; considering the importance of this issue, the aim of this study is to review all the studies related to alcohol and its relationship with metabolic syndrome and to update the information.

methodsPubMed, Scopus and Web of Science were searched to identify studies on the association between alcohol and metabolic syndrome from January 1, 2000 through August 13, 2023. The pooled OR and the 95% confidence intervals were used to measure the association between alcohol and metabolic syndrome by assuming a random effects meta-analytic model. Quality appraisal was undertaken using the Newcastle-Ottawa Scale.

resultsA total of 62 studies were included. In the association between use of alcohol and metabolic syndrome, the pooled OR for cross-sectional studies was 1.12 [95% CI: 1.07, 1.18] and the pooled OR for cohort studies was 1.12 [95% CI: 1.06, 1.18]. In cohort and cross-sectional studies, the association between alcohol dose and metabolic syndrome, was not significant. For the association between frequency of alcohol consumption and metabolic syndrome, the pooled OR for under 1 to 2 times a week, 2 times to 7 times a week and above 7 drink/week were 0.85 [95% CI: 0.78, 0.93], 0.80 [95% CI: 0.63, 1.01] and 1.02 [95% CI: 0.41, 2.56], respectively.

conclusionThis study showed a positive relationship between alcohol consumption and metabolic syndrome. Therefore, it is recommended that further studies be conducted to accurately evaluate alcohol consumption and metabolic syndrome components, and for evaluate reducing or stopping alcohol consumption on metabolic syndrome, it is better to conduct clinical trial studies in the future.

Indexed as

AlcoholMeta-analysisMetabolic syndromeSystematic review

Identifiers

PMID40604905
PMCPMC12220093

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.