Evidence map›Paper›PMID 40604847›Full record

Trial reportBMC oral health2025

Effectiveness of three manual toothbrushes with different bristle designs in terms of plaque removal and gingival inflammation: A randomized controlled trial.

Ratna Mishal, Ashish Shrestha, Tarakant Bhagat, Santosh Kumari Agrawal

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ratna MishalMadan Bhandari Hospital and Trauma Center, Urlabari, Nepal. ratnamishal18@gmail.com.
Ashish ShresthaDepartment of Public Health Dentistry, BPKIHS, Dharan, Nepal.
Tarakant BhagatDepartment of Public Health Dentistry, BPKIHS, Dharan, Nepal.
Santosh Kumari AgrawalDepartment of Public Health Dentistry, BPKIHS, Dharan, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlaque is causative factor for gingivitis and periodontitis. Mechanical plaque removal is one of most commonly used method. Toothbrush has many modifications since decade. New bristles claim to remove more plaque and improve oral hygiene. The objective was to assess the effectiveness of three different bristle designed toothbrushes in terms of plaque removal and gingival inflammation.

methodsA concurrent parallel randomized clinical trial was done among 105 female undergraduate medical students in which both examiner and analyser were blinded throughout the study period. The population was divided into three groups A, B and C (1:1:1) according to computer generated random list and assigned three different toothbrushes Oral B pro health (Crisscross), Oral B shiny clean toothbrush (Zigzag), Oral B sensitive care (Flat), respectively. Along with the toothbrushes, a fluoridated toothpaste was also provided. At baseline proper oral hygiene instruction and brushing method was demonstrated. Baseline plaque and gingival ghbvindex score was assessed by using Silness J and Loe H (1964) and Loe H and Silness J (1963), respectively. The follow up data collections were done at 7,14 and 21 days. Friedman's test was used to assess the association of plaque and gingival scores in different follow up. Pairwise PI and GI score were recorded and intergroup comparison of plaque and gingival scores were calculated by using Kruskal Wallis test.

resultThere were 35 participants allotted in each group. When compared to overall plaque and gingival score, there were significant reduction in every follow up (p < 0.001). However, Zigzag tooth brush showed more reduction in plaque and gingival score; mean rank scores were 38.69 and 26.56, respectively but it was not statistically significant (p > 0.05).

conclusionThis study showed that the three different toothbrushes were equally effective in plaque removal and reduction of gingival inflammation. The Zigzag toothbrush showed maximum reduction in plaque and gingival inflammation; however, the difference was not significant. CLINICAL

trial registrationThe study was retrospectively registered in ANZCTR on 21/02/2025 with trial registration number ACTRN12625000213448.

Indexed as

Dental PlaqueGingivitisToothbrushingAdultDental Plaque IndexEquipment DesignFemaleFollow-Up StudiesHumansOral HygienePeriodontal IndexSingle-Blind MethodToothpastesTreatment OutcomeYoung AdultToothpastesBristle designGingivitisManual toothbrushesPlaque

Identifiers

PMID40604847
PMCPMC12224694

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.