Evidence map›Paper›PMID 40604758›Full record

ArticleBMC oral health2025

Comparison of the effectiveness of the new generation dual wavelength laser with the conventional laser type in treating rabbit model temporomandibular joint osteoarthritis.

Gizemnur Karadayı, Nihat Akbulut, Faik Alev Deresoy, Ahmet Altan

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gizemnur KaradayıOral and Maxillofacial Surgeon, T.R. Ministry of Health, Oral and Dental Health Hospital, Çorum, Turkey.ORCID http://orcid.org/0000-0002-4871-0226
Nihat AkbulutDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ondokuz Mayıs University, Samsun, Turkey.ORCID http://orcid.org/0000-0001-6950-8214
Faik Alev DeresoyDepartment of Pathology, Kesan State Hospital, Edirne, Turkey.ORCID http://orcid.org/0000-0002-2243-9394
Ahmet AltanDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Necmettin Erbakan University, Konya, Turkey. dt.ahmetaltan@gmail.com.ORCID http://orcid.org/0000-0003-2041-6364

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study compared the effects of low-level laser applications with different wavelengths on rabbits' temporomandibular joint regeneration capacity with experimentally induced osteoarthritis.

methodsThis study used 23 male New Zealand white rabbits. The animals were randomly divided into three groups. Osteoarthritis was induced in all groups by injecting sodium monoiodoacetate into the rabbits' joints. The joints of the experimental animals in Group 1 (GRR laser-dual wavelength, n = 8) and Group 2 (Epic10 laser-conventional laser, n = 8) were treated with laser for 14 sessions. In the control group (n = 7), no treatment was performed after osteoarthritis was induced. After the end of laser therapy, the rabbits were sacrificed simultaneously, and the temporomandibular joints were removed. Defect filling percentage, osteochondral junction reconstruction, matrix staining, and cellular morphology were examined histopathologically.

resultsThere was a connection between the groups with defect filling, and a statistically significant difference was found (p = 0.005). When we examined whether there was a connection between the osteochondral junction and the groups, it was determined that there was no statistically significant connection (p = 1.000). It was determined that there was a significant connection between the groups with matrix staining (p = 0.001). There was a connection between cellular morphology and the groups. It was determined that there was a statistically significant connection (p = 0.018). The defect filling, matrix staining, and cellular morphology values in both laser groups were better than in the control group.

conclusionsLow-level laser therapy can increase remodeling and improve tissue repair in temporomandibular joint osteoarthritis treatment. There was no significant difference between lasers at different wavelengths in treating temporomandibular joint osteoarthritis.

Indexed as

Low-Level Light TherapyOsteoarthritisTemporomandibular Joint DisordersAnimalsCartilage, ArticularDisease Models, AnimalMaleRabbitsRandom AllocationRegenerationTemporomandibular JointLow-level laser therapyOsteoarthritisTemporomandibular joint disorders

Identifiers

PMID40604758
PMCPMC12220581

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.