Evidence map›Paper›PMID 40604709›Full record

ArticleBMC oral health2025

The impact of fluorinated graphene versus nanohydroxyapatite crystals on artificial white spot lesion microhardness and color change.

Sarah Diaa Shaheen, Mona Rizk Aboelwafa

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarah Diaa ShaheenLecturer of Conservative Department, College of Oral and Dental Surgery, Misr University for Science and Technology (MUST), Giza, Egypt. sarah.shaheen@must.edu.eg.
Mona Rizk AboelwafaDepartment of Operative Dentistry, Faculty of Dentistry, Sinai University - Kantara branch, Ismailia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the impact of the fluorinated graphene oxide nanosheets (FG) and nanohydroxyapatite (n-HAp) with and without microabrasion pretreatment on the cross sectional microhardness (CSMH) and color change (ΔE00) of artificially established white spot lesions. MATERIALS AND

methodsDemineralized eighty bovine enamel samples were splited into two groups (n = 40) based on the remineralizing material (n-HAp or FG), subsequently divided into two subgroups (n = 20) dependent on microabrasion pretreatment. The samples are remineralized for thirty days. ΔE00, elemental analysis employing energy-dispersive X-ray spectroscopy (EDX) along with surface features with scanning electron microscopy (SEM) was assessed. CSMH was measured at 50, 100, and 150 μm enamel depths. Statistical analysis was performed using ANOVA and post-hoc testing (p < 0.05).

resultsFG had the highest CSMH at 100 and 150 μm depths while microabrasion with remineralizing has a highest CSMH at 50 μm. EDX revealed that FG-treated specimens had the highest Ca/P ratio (p < 0.001). FG had the highest ΔE00, whereas microabrasion with n-HAp showed the least ΔE00.

conclusionsFG provides greater aesthetic enhancement and remineralization than n-HAp. microabrasion did not significantly boost the remineralization. CLINICAL SIGNIFICANCE: Fluorinated graphene oxide nanosheets are a promising remineralization approach for treating white spot lesions offering improved mineral recovery and aesthetic outcomes.

Indexed as

Dental CariesDental EnamelDurapatiteGraphiteTooth RemineralizationAnimalsCarbon NanomaterialsCattleColorHardnessMicroscopy, Electron, ScanningNanostructuresSpectrometry, X-Ray EmissionDurapatiteGraphiteCross-Sectional microhardness (CSMH)Fluorinated graphene oxide nanosheets (FG)Nano-Hydroxyapatite (nHA)White spot lesions

Identifiers

PMID40604709
PMCPMC12225187

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.