Evidence map›Paper›PMID 40604689›Full record

ArticleBMC musculoskeletal disorders2025

Management of pathologic fracture of long bones as a complication of acute osteomyelitis: a challenging task for orthopedic surgeons.

Ramin Zargarbashi, Fardis Vosoughi, Farhad Shaker, Mozhgan Seifi, Mona Mirbeyk, Amir R Vafaee

Abstract read
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Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ramin ZargarbashiDepartment of Pediatric Orthopedy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0001-8332-6353
Fardis VosoughiDepartment of Orthopaedic and Trauma Surgery, School of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. fardis.vosoughi@gmail.com.ORCID http://orcid.org/0000-0002-9136-0479
Farhad ShakerDepartment of Orthopaedic and Trauma Surgery, School of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0009-0003-5987-9873
Mozhgan SeifiDepartment of Pediatric Orthopedy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mona MirbeykDepartment of Immunology, Children's Medical Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-7405-3397
Amir R VafaeeDepartment of Pediatric Orthopedy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe management of pathologic fractures (PF) following osteomyelitis (especially the acute subtype) has not been widely investigated. Therefore, this study aims to assess a stepwise treatment plan for the acute incidence of PF in long bones following pediatric acute Hematogenous osteomyelitis (AHO).

methodsThis case series was conducted between 2011 and 2023 in a tertiary pediatric center. Patients with fracture incidence within the first 10 days after AHO diagnosis were included. Patients' characteristics were retrospectively reviewed. Our stepwise treatment plan was as follows: 1. Intravenous antibiotics until ESR<20, then oral to ESR<5 2. Debridement surgery was performed if abscesses were detected. 3. Fracture type determined initial fixation: external fixation or casting. 4. If the union was not obtained, internal fixation (with or without bone graft) was applied 5. Circular external fixation was applied if the union was not obtained or the leg length discrepancy occurred.

resultsEight patients (6 boys) with a mean age of 32.1 ± 26.7 months and a follow-up time of 8.64 ± 1.95 years were included. The etiology in all patients was hematological Methicillin-resistant Staphylococcus aureus. Except for one patient who died of septic shock, all other patients (87.5%) reached complete recovery (average length of hospital stay of 19.9 days) and obtained union with an average union time of 14.6 months. A mean of 1.25 surgical procedures, ranging from 0 to 4, were required to obtain union.

conclusionThe outcome of the stepwise plan in this study suggests that acute PF following AHO in pediatrics can be managed effectively with favorable clinical and functional outcomes in the mid- and long-term.

Indexed as

Fractures, SpontaneousOrthopedic SurgeonsOsteomyelitisAcute DiseaseAnti-Bacterial AgentsChildChild, PreschoolDebridementFemaleFollow-Up StudiesFracture Fixation, InternalHumansInfantMaleMethicillin-Resistant Staphylococcus aureusRetrospective StudiesAnti-Bacterial AgentsAcute fractureMRSAOsteomyelitisPathologic fracturePediatric

Identifiers

PMID40604689
PMCPMC12220615

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