ArticleBMC pediatrics2025
Metabolic evaluation and disease characteristics of urolithiasis in children from 2020 to 2024: a retrospective single-center study at the national children's medical center.
Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveTo analyze the composition and disease characteristics of pediatric urolithiasis in a single center, providing a scientific basis for clinical diagnosis, treatment, and prevention.
methodsThis study included 266 pediatric patients with urolithiasis admitted from September 2020 to September 2024. Composition analysis was conducted on 174 stone samples using infrared spectroscopy, and 24-h urinary metabolic evaluations were performed on 124 patients. Additionally, genetic testing was conducted on 18 patients using the GenCap panel to explore the role of genetic factors in stone formation.
resultsCalcium oxalate stones were the most common type, accounting for 63.2% of all stones, followed by calcium phosphate and carbonate apatite stones. The high-incidence age range for stones was 6-12 years, with a male-to-female ratio of 1.86:1. The 24-h urinary metabolic analysis revealed that urinary components such as calcium, oxalate, and uric acid were closely related to stone formation. Genetic testing identified multiple different genes associated with stone formation, further confirming the importance of genetic factors.
conclusionThe formation of pediatric urolithiasis is influenced by various factors, including metabolic abnormalities, urinary components, and genetic factors. Understanding these influencing factors contributes to the development of personalized prevention and treatment plans, reducing the recurrence rate and complications of stones.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.