SynthesisBMC public health2025
The effect of low-fat diets on appetite: a systematic review of randomized clinical trials.
Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Moderate increase in dietary fat induces alterations of microbiota and metabolome along the digestive tract prior to systemic metabolic changes: insights from a pig model.Gut microbes · 2025Article
- Therapeutic Potential of White Kidney Beans (Foods (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdherence to low-fat (LF) diets may be inversely associated with appetite; however, findings from available randomized controlled trials (RCTs) are conflicting. The present study aimed to systematically review RCTs assessing the effects of LF diets on appetite status in adult participants.
methodsWe searched PubMed, Scopus, Web of Science, and the Cochrane Library from the inception of the database to June 2, 2024, for RCTs that evaluated the effects of LF diets (≤ 30% total energy from fat), versus high-fat (HF, > 30% total energy from fat) diets on appetite status. No language restrictions were applied.
resultsInitially, 2471 articles were identified, of which nine studies met the inclusion criteria. Seven studies examined the effect of LF diets on hunger response, three of which reported a significantly lower hunger response. LF diets did not exert an effect on satiety, desire to eat, and palatability. Only one study showed that the LF diet, compared to the HF diet, had greater decreases in their total appetite score over a 6-month period.
conclusionsWe found that there were little or no additional benefits in changes to appetite status following LF diets in adults. However, due to methodological factors, shortcomings among studies and small number of studies, the current evidence on the effect of LF diets on appetite regulation is poor. Further long-term trials are needed to investigate the effect of LF diets on appetite and appetite-regulating hormones.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.