Evidence map›Paper›PMID 40604619›Full record

ArticleBMC pediatrics2025

Feasibility, acceptability and effectiveness of asthma education delivered by community health workers in improving asthma control in children and adolescents: a protocol for a cluster-randomized trial in Uganda.

Rebecca Nantanda, Levicatus Mugenyi, Andrew Sentoogo Ssemata, Sarah Namusoko, Phiona Ekyaruhanga, Mary Kuteesa, Fred Matovu, Jonathan Grigg

Abstract readClinical Trial Protocol
In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rebecca NantandaMakerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda. rnantanda@gmail.com.
Levicatus MugenyiMakerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Andrew Sentoogo SsemataMRC/ UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda.
Sarah NamusokoMakerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Phiona EkyaruhangaMakerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Mary KuteesaMakerere University Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Fred MatovuSchool of Economics, College of Business and Management Sciences, Makerere University Kampala, Kampala, Uganda.
Jonathan GriggCentre for Genomics and Child Health, School of Medicine and Dentistry, Blizard Institute, Barts and The London, Queen Mary University of London, London, UK.

Funding

UK Medical Research Council (MRC) and the UK Foreign, Commonwealth & Development Office (FCDO) MR/X031713/1
6 · The paper itself

Abstract

backgroundAsthma control is a major challenge particularly in low and middle-income countries where access to care is still poor. Asthma education is a cornerstone in self-management and achieving asthma symptom control. However, there is limited human resources to offer asthma education in low-resources settings. This study will investigate the feasibility, acceptability and effectiveness of community health worker (CHW)-led asthma education in improving asthma control among children and adolescents in Uganda.

methodsThe study will employ a cluster-randomized trial (CRT) study design. It will be conducted in 8 primary care health facilities (HFs) in Jinja region, Eastern Uganda. The HFs will be randomly assigned to the control and intervention arms in the ratio 1:1. The sample size will be 300 children (150 per arm), and asthma control, emergency care visits and hospitalizations will be assessed at baseline, month 1,3 and 6. Asthma education will be provided by CHWs known as Village Health Teams (VHTs) at each visit. Data on direct and indirect costs of asthma education will be collected prospectively. Focus Group Discussions (FGDs) will be conducted among VHTs and caregivers of participating children at the intervention sites to assess the feasibility and acceptability of the intervention. To estimate the mean difference in asthma control scores between the intervention and control arms, adjusted for baseline scores and facility-level clustering, we shall use a random-effects linear regression model and intention-to-treat analysis. The primary endpoint will be asthma control scores. Cost-effectiveness will be assessed by computing the Incremental Cost-Effectiveness Ratio. Thematic content analysis will be used to analyze data from the FGDs. DISCUSSION: It is anticipated that the study will provide evidence about the role of community health workers in supporting the care of patients with asthma and achieving symptom control, through providing health education. The data on feasibility, acceptability and cost-effectiveness will be critical in informing scale up plans. TRIAL REGISTRATION NUMBER: ISRCTN16018011. Date: 25/05/2024.

Indexed as

AsthmaCommunity Health WorkersPatient Education as TopicAdolescentChildCost-Benefit AnalysisFeasibility StudiesFemaleHumansMaleRandomized Controlled Trials as TopicUgandaAsthmaChildren adolescentsCommunity health workersEducation

Identifiers

PMID40604619
PMCPMC12220509

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.