Evidence map›Paper›PMID 40604573›Full record

ArticleBMC neurology2025

Optimal timing for tracheostomy in severe ischemic stroke patients: early or standard incision?

Chutong Guo, Heng Ye, Xinglin Chen, Yuting Luo, Shaoqing Wu, Xunsha Sun

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Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Chutong Guo *Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases; National Key Clinical Department and Key Discipline of Neurology, No.58 Zhongshan Road 2, Guangzhou, 510080, China.
Heng Ye *Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases; National Key Clinical Department and Key Discipline of Neurology, No.58 Zhongshan Road 2, Guangzhou, 510080, China.
Xinglin ChenDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases; National Key Clinical Department and Key Discipline of Neurology, No.58 Zhongshan Road 2, Guangzhou, 510080, China.
Yuting LuoDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases; National Key Clinical Department and Key Discipline of Neurology, No.58 Zhongshan Road 2, Guangzhou, 510080, China.
Shaoqing WuGuangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. wsqone@163.com.
Xunsha SunDepartment of Neurology, The First Affiliated Hospital, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases; National Key Clinical Department and Key Discipline of Neurology, No.58 Zhongshan Road 2, Guangzhou, 510080, China. sunxsh3@mail.sysu.edu.cn.

Funding

Guangdong Province International Cooperation Base for Early Intervention and Functional Rehabilitation of Neurological Diseases 2020A0505020004Guangdong Provincial Clinical Research Center for Neurological Diseases 2020B1111170002he National Natural Science Foundation of China 82271333Kelin New Talent Program R08016Science and Technology Projects in Guangzhou 202201020652the National Natural Science Foundation of China 82071292
6 · The paper itself

Abstract

backgroundTracheostomy is frequently performed in severe ischemic stroke patients, yet the ideal timing for this procedure remains undefined. This study seeks to inform clinical decisions by evaluating the impact of early versus standard tracheostomy on clinical outcomes in this patient population.

methodsWe retrospectively reviewed severe ischemic stroke patients who underwent tracheostomy at our hospital between January 2013 and November 2023. Patients were categorized into early tracheostomy (ET) and standard tracheostomy (ST) groups based on the interval from intubation to tracheostomy. Clinical outcomes were compared between the two groups. The logistic regression model was used to assess the correlation between the timing of tracheostomy and outcomes, and the Kaplan-Meier method was employed to analyze time-to-event results.

resultsThe study encompassed 110 patients, with 57 in the ET group and 53 in the ST group. The results showed that the ET group had a longer interval from onset to intubation (P = 0.048), but there was no significant difference in the proportion of patients with severe disability after six months (OR 1.089 [95% CI 0.377-3.144], aOR 1.091 [95% CI 0.345-3.447]). The ET group demonstrated a shorter mechanical ventilation time (aOR 1.036 [95%CI 1.005-1.069]) and a decreased incidence of tracheostomy-related complications (aOR 5.378 [95%CI 1.065-27.144]).

conclusionEarly tracheostomy does not affect the long-term outcomes of patients with severe ischemic stroke, but it may offer potential benefits.

Indexed as

Ischemic StrokeTime-to-TreatmentTracheostomyAgedAged, 80 and overFemaleHumansMaleMiddle AgedRespiration, ArtificialRetrospective StudiesTime FactorsTreatment OutcomeAcute StrokeAirway ManagementEarly TracheostomyIntensive CareIschemic StrokeTracheostomy

Identifiers

PMID40604573
PMCPMC12219337

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.