Evidence map›Paper›PMID 40604548›Full record

ArticleBMC public health2025

Long-term air pollution exposure and cardiovascular disease risk across cardiovascular-renal-metabolic stages: a nationwide study.

Leying Zhao, Cong Zhao, Weiwei Sun, Huijuan Zheng, Yabin Gao, Chan Kam Wa, Qiong Wang, Qingqing Liu, Yaoxian Wang, Zhen Wang

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leying Zhao *Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Cong Zhao *Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Weiwei SunDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Huijuan ZhengDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Yabin GaoDepartment of Nephropathy, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Chan Kam WaSchool of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China.
Qiong WangCDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Qingqing LiuDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Yaoxian WangDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China. 201903001@bucm.edu.cn.
Zhen WangDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China. zhenwangdzm@126.com.

Funding

Beijing University of Chinese Medicine's-2022-Basic-Research-Business Fee Disclosure Leading Project Grant No. 2022-JYB-JBZR-038Chinese Medicine Inheritance and Innovation Talent Project-Leading Talent Support Program of National Traditional Chinese Medicine Grant No. 2018, No. 12
6 · The paper itself

Abstract

backgroundCardiovascular-renal-metabolic (CKM) syndrome substantially elevates the risk of cardiovascular disease (CVD). Environmental air pollution, especially particulate matter (PM), is a key contributor, yet its long-term effects across CKM stages remain unclear.

objectivesThis study aimed to evaluate the association between long-term exposure to different sizes of particulate matter (PM

methodsWe conducted a nationwide prospective cohort study using data from the China Health and Retirement Longitudinal Study (CHARLS, 2011-2018), including 5,824 participants aged 45 years or older. CKM stages (0 to 3) were classified according to American Heart Association guidelines. Annual average concentrations of PM

resultsDuring a median follow-up of 7 years, participants in the highest exposure group of PM

conclusionsLong-term exposure to ambient particulate matter significantly increases CVD risk, especially among individuals in advanced CKM stages. IMPLICATIONS: These findings support incorporating CKM staging into environmental health risk assessments and highlight the need for targeted cardiovascular screening and pollution control strategies in high-exposure regions. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Air PollutionCardiovascular DiseasesEnvironmental ExposureMetabolic SyndromeParticulate MatterAgedChinaFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesParticulate MatterAir pollutionCardiovascular diseaseCardiovascular-renal-metabolic syndromeLong-term exposure

Identifiers

PMID40604548
PMCPMC12220752

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.