ArticleBMC geriatrics2025
Sarcopenic obesity is linked to worse clinical outcomes than sarcopenia or obesity alone in hospitalized older adults.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Stress biology and metabolic ageing in older adults during prolonged crises: Ukraine as an example.Biogerontology · 2026Review
- Candidate Circulating microRNAs in Patients with Sarcopenic Obesity: Results of a Pilot Screening.Biomedicines · 2026Article
- Interplay between sarcopenia and type 2 diabetes: mechanisms, implications, and therapeutic prospects.Nutrition & diabetes · 2026Review
- Prehabilitation in Obese Patients with Ventral Hernia: A Narrative Review and Proposal of a Clinical Algorithm.Journal of clinical medicine · 2026Review
- Assessing the risk of sarcopenia among community-dwelling older adults in Israel: a national cross-sectional survey.European geriatric medicine · 2026Article
- Exploring the nexus between inflammation and mobility through the lens of healthy aging: current scenario and future perspectives.Aging clinical and experimental research · 2026Review
- Declines in Activities in Daily Living of Older Adults with Sarcopenia Were Associated with Gait Speed.Medicina (Kaunas, Lithuania) · 2026Article
- Sarcopenia, Obesity, and Sarcopenic Obesity in Relation to Functional Limitations in Older Adults.Journal of clinical medicine · 2026Article
- Unseen and untreated: implementing sarcopenic obesity care in Nordic general practice.Frontiers in aging · 2026Article
- Peri-operative nutrition in femoral neck fracture arthroplasty: a pragmatic framework to mitigate dual-hit catabolism and improve outcomes.Orthopedic reviews · 2026Article
- Intermittent fasting and immune aging: implications for immunosenescence, inflammaging, neuroinflammation, and frailty.Frontiers in nutrition · 2026Review
- Advancing Precision Diagnosis of Sarcopenic Obesity Through Digital Technologies, Wearables and Omics Data.Life (Basel, Switzerland) · 2025Review
- Aging-Related Obesity: Unveiling Mitochondrial and Metabolic Dysfunction.Current nutrition reports · 2025Review
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Abstract
backgroundSarcopenic obesity (SO), the coexistence of low muscle mass and excess fat, is increasingly recognized in older adults. Its definition and clinical implications remain debated. This study evaluated SO using the European Society for Clinical Nutrition and Metabolism-European Association for the Study of Obesity (ESPEN-EASO) criteria and examined its associations with geriatric syndromes and metabolic risk factors.
methodsWe conducted a retrospective cross-sectional study of 364 hospitalized patients aged ≥ 65 years who underwent bioelectrical impedance analysis. Geriatric assessments included Activities of Daily Living (ADL), Instrumental ADL (IADL), Mini Nutritional Assessment-Short Form (MNA-SF), Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS), Clinical Frailty Scale (CFS), and handgrip strength. Mortality data were collected. Associations with SO were analyzed using univariate and multivariate logistic regression.
resultsSO prevalence was 24.5%. Patients with SO had worse ADL, IADL, MNA-SF scores, and lower handgrip strength (all p < 0.01). Independent predictors of SO included older age (OR = 1.064, p = 0.002), female gender (OR = 3.574, p < 0.001), hypertension (OR = 2.094, p = 0.007), and diabetes mellitus (OR = 3.342, p < 0.001). The SO group had higher mortality (15.1% vs. 9.3%, p = 0.03). A geriatric model including frailty, MNA-SF (OR = 0.472, 95% CI: 0.306-0.727), and handgrip strength (OR = 0.741, 95% CI: 0.641-0.856) showed better model fit (Nagelkerke R² = 0.474) than the metabolic model (R² = 0.223).
conclusionSO is a distinct clinical condition linked to frailty, functional decline, and mortality. Geriatric factors show stronger associations than metabolic indicators, underscoring the importance of comprehensive geriatric screening in older adults. CLINICAL
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