Trial reportBMC primary care2025
Effectiveness of digital platform in reducing unintentional medication discrepancies at transition of care from hospital discharge to primary healthcare settings: a randomised controlled trial.
Trial report in BMC primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06517160 (A Randomised Controlled Trial to Compare MedBook Portal and Standard Care in Medication Reconciliation at Transitions of Care From Hospital Discharge to Primary Healthcare Settings), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomised Controlled Trial to Compare MedBook Portal and Standard Care in Medication Reconciliation at Transitions of Care From Hospital Discharge to Primary Healthcare Settings
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundModifications to medication regimens during transitions of care between different healthcare settings often lead to unintentional medication discrepancies (UMDs). The MedBook Portal, a simple digital platform that enables the sharing of patient medication records among healthcare facilities under Ministry of Health, was developed to facilitate medication reconciliation at primary health clinic (PHC) after hospital discharge. This study aimed to determine the effectiveness of MedBook Portal in reducing UMDs in the first prescription during the first PHC visit after hospital discharge.
methodsThis two-arm, parallel, non-blinded, randomised controlled trial was conducted at four public hospitals and ten public PHCs in Sarawak, Malaysia, from May 2023 to July 2024. Adult patients aged ≥ 18 years in general medical wards, discharged from hospitals, and referred to selected PHCs were recruited. In the Standard Care group, PHC doctors performed standard medication reconciliation by reviewing patients' medical records on their home-based medical cards and discharge notes, if available. In the MedBook Portal group, in addition to this process, PHC doctors logged into MedBook Portal to access the discharge prescription before issuing a new prescription.
resultsAmong the 339 eligible subjects randomised into MedBook Portal group and Standard Care group, 307 participants (147 MedBook Portal, 160 Standard Care) were analysed after excluding those for whom the intervention was not performed (n = 11) and those with no prescription (n = 21). The incidence rate of prescription with UMDs was significantly lower in the MedBook Portal group (5/147, 3.4%) compared to the Standard Care group (30/160, 18.8%) (p < 0.001). The most common UMD was drug omission (54.4%). Multivariable logistic regression showed that the presence of MedBook Portal reduced the odds of UMDs by 87% (adjusted OR 0.134, 95% CI 0.049-0.336, p < 0.001), whereas each additional comorbidity increased the odds by 52% (adjusted OR 1.520, 95% CI 1.158-2.020, p = 0.003).
conclusionsMedication reconciliation using the MedBook Portal effectively reduces UMDs during the transition of care from hospital discharge to PHCs, enhancing patient safety across the continuum of care.
trial registrationClinicalTrials.Gov (NCT06517160) was registered retrospectively on 19 September 2024.
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