Evidence map›Paper›PMID 40604485›Full record

ArticleBMC primary care2025

Tailoring remote patient management to optimise cardiovascular risk management in primary care: a mixed-methods implementation study informing large-scale implementation.

Margot Rakers, Nicoline van Hattem, Eric Hiddink, Petra van Peet, Rimke Vos, Niels Chavannes, Douwe Atsma, Tobias Bonten, Hendrikus van Os

Abstract read
In one paragraph

Article in BMC primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Margot RakersDepartment of Public Health and Primary Care, Leiden University Medical Center, 2333 ZA, Leiden, the Netherlands. m.m.rakers@lumc.nl.
Nicoline van HattemDepartment of Public Health and Primary Care, Leiden University Medical Center, 2333 ZA, Leiden, the Netherlands.
Eric HiddinkDepartment of Public Health and Primary Care, Leiden University Medical Center, 2333 ZA, Leiden, the Netherlands.
Petra van PeetDepartment of Public Health and Primary Care, Leiden University Medical Center, 2333 ZA, Leiden, the Netherlands.
Rimke VosNational eHealth Living Lab (NeLL), Leiden University Medical Center, Albinusdreef 2, ZA, Leiden, 2333, the Netherlands.
Niels ChavannesDepartment of Public Health and Primary Care, Leiden University Medical Center, 2333 ZA, Leiden, the Netherlands.
Douwe AtsmaNational eHealth Living Lab (NeLL), Leiden University Medical Center, Albinusdreef 2, ZA, Leiden, 2333, the Netherlands.
Tobias BontenDepartment of Public Health and Primary Care, Leiden University Medical Center, 2333 ZA, Leiden, the Netherlands.
Hendrikus van OsDepartment of Public Health and Primary Care, Leiden University Medical Center, 2333 ZA, Leiden, the Netherlands.

Funding

Innovative Medical Devices Initiative (IMDI) LSHM21009
6 · The paper itself

Abstract

aimRemote patient management (RPM) effectively aids cardiovascular risk management, but its large-scale implementation remains challenging. Panel management may facilitate implementation by using comprehensive data to identify patients at risk of cardiovascular diseases and tailor interventions. This study evaluated the implementation strategies and clinical outcomes of a multi-component RPM intervention 'Connect@Heart'.

methodsWe conducted a mixed-methods study over six months in four primary care practices in the Netherlands, evaluating two patient groups: (i) patients with a BMI < 25 received a blood pressure monitor alone (BP Box), and (ii) patients with a BMI > 25 or cardiovascular disease received a combination of a BP monitor, a scale, and an activity tracker (Lifestyle Box). Baseline and six-month follow-up assessments were performed using linear mixed-effects models, and implementation outcomes were evaluated using the RE-AIM framework.

resultsOur approach achieved high enrolment, with 189 out of 200 initially interested patients (94%) participating. The intervention was associated with a significant reduction in BP levels within both groups (BP Box systolic BP from 139 ± 21 mmHg at baseline to 132 ± 18 mmHg at follow-up, p < 0.001 and Lifestyle Box 142 ± 16 mmHg to 131 ± 14 mmHg at follow-up, p < 0.001), especially for those with uncontrolled hypertension. After six months, 66% of patients performed measurements weekly. All participating practices continued using the intervention post-study.

conclusionThis study demonstrates that proactively identifying patient panels at risk for CVD and tailoring multi-component RPM interventions to patient panels are promising implementation strategies for reaching favourable clinical outcomes at scale.

Indexed as

Cardiovascular DiseasesPrimary Health CareRisk ManagementAgedBody Mass IndexFemaleHumansMaleMiddle AgedNetherlandsTelemedicineBlood pressureCardiovascular riskPanel managementRemote patient managementTailoring devices

Identifiers

PMID40604485
PMCPMC12220195

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.