ArticleBMC pediatrics2025
The association between short-term postoperative complications and bowel function after surgery for Hirschsprung disease.
Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Association Between Perioperative Inflammatory Trajectories and Postoperative Hirschsprung-Associated Enterocolitis: Insights from Group-Based Trajectory Modeling.Journal of inflammation research · 2026Article
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Authors and funding
8 authors.
Funding
Abstract
objectiveThis study aims to investigate the relationship between postoperative short-term complications and bowel function in patients with Hirschsprung disease (HSCR), and to explore the risk factors affecting bowel function.
methodsThe medical records of 367 eligible patients diagnosed with HSCR were reviewed. According to the bowel function score (BFS), patients were divided into a normal bowel function group (200 cases, BFS > 17) and an abnormal bowel function group (167 cases, BFS ≤ 17), and the possible risk factors for poor bowel function were evaluated through univariate and multivariate analysis. According to the Clavien Madadi (CM) classification of complications, CM grades I and II were considered mild complications and CM III and IV were considered severe complications.
resultsAccording to binary logistic regression analysis, long-segment disease (OR = 3.255; 95% CI, 1.192-9.655; p = 0.026), formula feeding (OR = 3.081; 95% CI, 1.626-5.933; p = 0.001), mild complications (OR = 9.560; 95% CI, 4.261-24.01; p < 0.001), and severe complications (OR = 17.127; 95% CI, 4.280-116.6; p < 0.001) were independent risk factors for postoperative poor bowel function. The surgery age between 1 and 3 years (OR = 0.357; 95% CI, 0.158-0.791; p = 0.012) was associated with a reduction in the incidence of poor bowel function.
conclusionsPostoperative complications, long-segment disease, and formula feeding are independent risk factors for postoperative poor bowel function in patients with HSCR. Further multicenter studies require larger sample sizes to clarify and confirm our findings.
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