Evidence map›Paper›PMID 40604478›Full record

Observational studyBMC geriatrics2025

Risk factors for death or serious adverse events within 3-month after surgery in frail older persons with hip fractures and development and validation of a risk prediction model: Based on LASSO-logistic regression.

Yaqi Guan, Lidan Zheng, Yipei Wang, Xiaoxiao Xu, Yueying Zhu

Abstract readObservational StudyValidation Study
In one paragraph

Observational study in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yaqi GuanDepartment of Joint and Trauma Surgery (Nursing Department), The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Lidan ZhengDepartment of Joint and Trauma Surgery (Nursing Department), The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Yipei WangDepartment of Joint and Trauma Surgery (Nursing Department), The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Xiaoxiao XuDepartment of Joint and Trauma Surgery (Nursing Department), The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Yueying ZhuDepartment of Joint and Trauma Surgery (Nursing Department), The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. zyy1202@126.com.

Funding

Wenzhou scientific research project Y20220523
6 · The paper itself

Abstract

backgroundThe number of frail older persons with hip fractures significantly increases. Some research indicated the incidence of mortality and adverse events for frail patients is higher than for non-frail patients. This article explores the incidence, development, and validation of a predictive model of serious adverse events and mortality in the 3-month following period.

methodsThis was an observational cohort study conducted at a tertiary hospital. Participants were consecutively admitted from December 2022 to August 2024. A total of 145 participants were included in this study. The LASSO regression and Cox proportional hazards regression analysis were developed to predict the model. Receiver operating characteristic (ROC) curves, Area under the curve (AUC), and C-index were used to assess model performance.

results26 (17.93%) patients have died or experienced serious adverse events after surgery in the 3-month follow up. The Cox proportional hazards regression analysis indicates age and the number of drugs for postoperative treatment are risk factors. Hemoglobin at admission and a high Barthel index of activities of daily living (before fracture two weeks) are protective factors. The model achieved a high AUC of 0.837 and a C-index of 0.772 (95% CI: 0.690-0.853). The sensitivity is 0.842 and the specificity is 0.675 which suggests great discrimination. The Hosmer-Lemeshow goodness-of-fit test shows X

conclusionsThis study indicates a high incidence of death or serious adverse events within 3-month after surgery in frail older persons with hip fractures. Age, the number of drugs for postoperative treatment, hemoglobin at admission, and Barthel index of activities of daily living (before fracture two weeks) are predictors. The nomogram helps healthcare to screen patients with high risk and to provide references for perioperative management and discharge care.

Indexed as

Frail ElderlyHip FracturesPostoperative ComplicationsAgedAged, 80 and overCohort StudiesFemaleHumansLogistic ModelsMaleRisk AssessmentRisk FactorsDeathFrail older personHip fracturesRegression analysisSerious adverse events

Identifiers

PMID40604478
PMCPMC12220730

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.