Evidence map›Paper›PMID 40604286›Full record

ArticleNature2025

Whole-genome ancestry of an Old Kingdom Egyptian.

Adeline Morez Jacobs, Joel D Irish, Ashley Cooke, Kyriaki Anastasiadou, Christopher Barrington, Alexandre Gilardet, Monica Kelly, Marina Silva, Leo Speidel, Frankie Tait and 11 more

Abstract readHistorical Article
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Adeline Morez JacobsSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK. adelinemorez@gmail.com.ORCID 0000-0003-2393-7931
Joel D IrishSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0001-7857-8847
Ashley CookeWorld Museum, National Museums Liverpool, Liverpool, UK.ORCID 0009-0008-1264-0095
Kyriaki AnastasiadouAncient Genomics Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0001-8033-6070
Christopher BarringtonBioinformatics and Biostatistics, The Francis Crick Institute, London, UK.ORCID 0000-0003-1281-2658
Alexandre GilardetAncient Genomics Laboratory, The Francis Crick Institute, London, UK.
Monica KellyAncient Genomics Laboratory, The Francis Crick Institute, London, UK.ORCID 0009-0006-7075-1290
Marina SilvaAncient Genomics Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0002-3756-0920
Leo SpeidelAncient Genomics Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0002-4644-8033
Frankie TaitAncient Genomics Laboratory, The Francis Crick Institute, London, UK.ORCID 0009-0004-1864-5867
Mia WilliamsAncient Genomics Laboratory, The Francis Crick Institute, London, UK.
Nicolas BrucatoCentre de Recherche sur la Biodiversité et l'Environnement (CRBE), Université de Toulouse, CNRS, IRD, Toulouse INP, Université Toulouse III-Paul Sabatier (UT3), Toulouse, France.
Francois-Xavier RicautCentre de Recherche sur la Biodiversité et l'Environnement (CRBE), Université de Toulouse, CNRS, IRD, Toulouse INP, Université Toulouse III-Paul Sabatier (UT3), Toulouse, France.ORCID 0000-0001-7609-7898
Caroline WilkinsonFace Lab, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0002-4603-5554
Richard MadgwickSchool of History, Archaeology and Religion, Cardiff University, Cardiff, UK.
Emily HoltSchool of History, Archaeology and Religion, Cardiff University, Cardiff, UK.ORCID 0000-0002-2300-2610
Alexandra J NederbragtSchool of Earth and Environmental Sciences, Cardiff University, Cardiff, UK.
Edward InglisSchool of Earth and Environmental Sciences, Cardiff University, Cardiff, UK.ORCID 0000-0002-4183-0663
Mateja HajdinjakAncient Genomics Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0002-4064-0331
Pontus SkoglundAncient Genomics Laboratory, The Francis Crick Institute, London, UK. pontus.skoglund@crick.ac.uk.ORCID 0000-0002-3021-5913
Linus Girdland-FlinkSchool of Biological and Environmental Sciences, Liverpool John Moores University, Liverpool, UK. linus.girdlandflink@abdn.ac.uk.ORCID 0000-0001-6499-8728

Funding

Cancer Research UK, the UK Medical Research CouncilLiverpool John Moores UniversitySir Henry Wellcome FellowshipWellcome Trust
6 · The paper itself

Abstract

Ancient Egyptian society flourished for millennia, reaching its peak during the Dynastic Period (approximately 3150-30 BCE). However, owing to poor DNA preservation, questions about regional interconnectivity over time have not been addressed because whole-genome sequencing has not yet been possible. Here we sequenced a 2× coverage whole genome from an adult male Egyptian excavated at Nuwayrat (Nuerat, نويرات). Radiocarbon dated to 2855-2570 cal. BCE, he lived a few centuries after Egyptian unification, bridging the Early Dynastic and Old Kingdom periods. The body was interred in a ceramic pot within a rock-cut tomb

Indexed as

DNA, AncientGenome, HumanWhole Genome SequencingAdultEgyptEgypt, AncientHistory, AncientHumansMalePhylogenyDNA, Ancient

Identifiers

PMID40604286
PMCPMC12367555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.