Evidence map›Paper›PMID 40604255›Full record

ArticleNPJ digital medicine2025

Clinical decision support using pseudo-notes from multiple streams of EHR data.

Simon A Lee, Sujay Jain, Alex Chen, Kyoka Ono, Arabdha Biswas, Ákos Rudas, Jennifer Fang, Jeffrey N Chiang

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Smart assistive technologies for neurodisorders: A review on AI, IoT, and wearable systems for enhanced patient care.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Simon A LeeDepartment of Computational Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Sujay JainDepartment of Computational Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Alex ChenDepartment of Computational Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Kyoka OnoDepartment of Computational Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Arabdha BiswasDepartment of Computational Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Ákos RudasDepartment of Computational Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Jennifer FangLA Health Services, Los Angeles, CA, USA.
Jeffrey N ChiangDepartment of Computational Medicine, University of California Los Angeles, Los Angeles, CA, USA. njchiang@g.ucla.edu.

Funding

Biomedical Data Science Training Program for Precision Health EquityT15LM013976 · NLM · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ALEX BUI · 2022 to 2026
$1.9M
NLM NIH HHS T15 LM013976
6 · The paper itself

Abstract

Electronic health records (EHR) contain data from disparate sources, spanning various biological and temporal scales. In this work, we introduce the Multiple Embedding Model for EHR (MEME), a deep learning framework for clinical decision support that operates over heterogeneous EHR. MEME first converts tabular EHR into "pseudo-notes", reducing the need for concept harmonization across EHR systems and allowing the use of any state-of-the-art, open source language foundation models. The model separately embeds EHR domains, then uses a self-attention mechanism to learn the contextual importance of these multiple embeddings. In a study of 400,019 emergency department visits, MEME successfully predicted emergency department disposition, discharge location, intensive care requirement, and mortality. It outperformed traditional machine learning models (Logistic Regression, Random Forest, XGBoost, MLP), EHR foundation models (EHR-shot, MC-BEC, MSEM), and GPT-4 prompting strategies. Due to text serialization, MEME also exhibited strong few-shot learning performance in an external, unstandardized EHR database.

Identifiers

PMID40604255
PMCPMC12222764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.