Evidence map›Paper›PMID 40604212›Full record

ArticleScientific reports2025

Morbidity patterns and long-term outcomes of central lymph node dissection in thyroid cancer patients.

Khalid Atallah, Shadi Awny, Khaled Abdelwahab, Ahmed Abdallah, Islam H Metwally, Omar Hamdy, Mohammed Zuhdy, Ahmed Fareed

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Khalid AtallahSurgical Oncology Department, Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Shadi AwnySurgical Oncology Department, Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Khaled AbdelwahabSurgical Oncology Department, Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Ahmed AbdallahSurgical Oncology Department, Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Islam H MetwallySurgical Oncology Department, Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Omar HamdySurgical Oncology Department, Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt. omarhamdy@mans.edu.eg.
Mohammed ZuhdySurgical Oncology Department, Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Ahmed FareedSurgical Oncology Department, Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central lymph node metastasis (CLNM) is observed in 20-90% of patients with differentiated thyroid cancer (DTC). Central lymph node dissection (CLND) is associated with a higher incidence of complications, including hypocalcemia and an increased risk of recurrent laryngeal nerve injury. This study aimed to characterize and analyze the morbidity of CLND precisely. This is a retrospective cohort study that included patients who were diagnosed with thyroid cancer and underwent total thyroidectomy and CLND at a tertiary cancer center from January 2012 to December 2023. Among 420 patients, intraoperative complications were observed in 47 patients (11.2%). The commonest was recurrent laryngeal nerve palsy, which occurred in 16 patients. Stridor was detected immediately after extubating five patients. The commonest postoperative complication was hypocalcemia, which occurred in 69 patients (16.4% of patients), 21 patients (5%) required hospital re-admission, and most of them were temporary (79.4%). CLND may lead to morbidity in 1 to 2 of every 10 patients. Better diagnostic tools and predictive models are mandatory to identify the central compartment disease burden. Moreover, more advanced surgical techniques are needed to spare the patients the potential complications.

Indexed as

Lymph Node ExcisionThyroid NeoplasmsAdultAgedFemaleHumansHypocalcemiaLymphatic MetastasisMaleMiddle AgedMorbidityPostoperative ComplicationsRecurrent Laryngeal Nerve InjuriesRetrospective StudiesThyroidectomyTreatment OutcomeCentral lymph node dissectionHypocalcemiaMedullary thyroid carcinomaPapillary thyroid carcinomaRecurrent laryngeal nerve injuryThyroid cancer

Identifiers

PMID40604212
PMCPMC12222766

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.