ArticleScientific reports2025
Antimicrobial stewardship reduces antibiotic use density and cost in a Chinese tertiary hospital.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Development and applicability assessment of a 5R-principle-guided evaluation system for antimicrobial stewardship in open extremity trauma using a hybrid Delphi-analytic hierarchy process model.Frontiers in cellular and infection microbiology · 2026Article
- Impact of an antimicrobial stewardship-based infection prevention bundle on postoperative central nervous system infection in a tertiary neurosurgery department: a quasi-experimental study.Frontiers in pharmacology · 2026Article
- Combating Antimicrobial Resistance: A Pharmacist-Led PDCA Stewardship Program in a Tertiary Hospital.Infection and drug resistance · 2026Article
- Enhancing antimicrobial stewardship through IT-enabled audits: a quasi-experimental study in urology.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
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14 authors.
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Abstract
Antimicrobial Stewardship Programs (ASP) have demonstrated efficacy in lowering hospital expenditures and enhancing the judicious use of antibiotics. However, many hospitals in China have not yet established an ASP management model, and there is limited literature reporting successful ASP experiences. This study aimed to investigate the impact of ASP on Antibiotics Use Density (AUD). We conducted a retrospective study from October 2023 to September 2024 in a tertiary general hospital in Hangzhou, China. Based on audits of antibiotic orders conducted from October 1, 2023, to March 31, 2024, we identified potential factors contributing to high AUD. In line with the guidelines for implementing ASP, we established an ASP team and implemented comprehensive improvement strategies from April 1, 2024, to September 30, 2024. Following the implementation of ASP, the AUD decreased significantly by 31.01% from 54.20 prior to intervention to 37.39 post-intervention. The total Defined Daily Doses (DDD
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