ArticleScientific reports2025
Jackalope Plus tool for post-coordination, ontology development, and precise mapping in observational health studies.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Accurate mapping of complex health data to the OMOP CDM while preserving clinical nuance remains a challenge. We introduce Jackalope Plus, a novel tool leveraging SNOMED CT post-coordination and a GPT-4o mini LLM, to significantly enhance the precision and efficiency of this process. Our two-step approach combines semantic search with LLM-driven standardization, enabling accurate conversion of intricate medical concepts. Evaluation on benchmark and custom datasets demonstrates that Jackalope Plus identifies correct mappings for over 77.5% of complex terminologies, substantially outperforming Usagi (52.5%) and matching the accuracy of manual mapping while offering up to 50% time savings. Jackalope Plus offers a versatile solution for diverse healthcare data environments. Future work will focus on refining the tool through user feedback integration and addressing ambiguities in overlapping concepts. A free beta version is available for research and feedback. Ethical review confirms no storage of patient-identifiable information.
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