Evidence map›Paper›PMID 40603873›Full record

ArticleScientific reports2025

Comparative phytochemical analysis and bioactive potential of white and black garlic.

Hatice Kubra Sasmaz, Ceren Ilgaz, Pınar Kadiroglu, Ozgür Cem Erkin, Serkan Selli, Hasim Kelebek

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hatice Kubra SasmazDepartment of Food Engineering, Faculty of Engineering, Adana Alparslan Turkes Science and Technology University, 01250, Adana, Türkiye.
Ceren IlgazDepartment of Food Engineering, Faculty of Engineering, Adana Alparslan Turkes Science and Technology University, 01250, Adana, Türkiye.
Pınar KadirogluDepartment of Food Engineering, Faculty of Engineering, Adana Alparslan Turkes Science and Technology University, 01250, Adana, Türkiye.
Ozgür Cem ErkinDepartment of Bioengineering, Faculty of Engineering, Adana Alparslan Turkes Science and Technology University, 01250, Adana, Türkiye.
Serkan SelliDepartment of Food Engineering, Faculty of Engineering, Cukurova University, 01330, Adana, Türkiye.
Hasim KelebekDepartment of Food Engineering, Faculty of Engineering, Adana Alparslan Turkes Science and Technology University, 01250, Adana, Türkiye. hkelebek@atu.edu.tr.

Funding

Scientific and Technological Research Council of Türkiye (TUBITAK) TOVAG 219O174
6 · The paper itself

Abstract

The phenolic and organosulfur compound profiles of black garlic samples produced at different temperatures, humidity and durations were determined using liquid chromatography-electrospray tandem mass spectrometry (LC-ESI-MS/MS) and their bioactive properties were compared with those of the white garlic samples. The total concentrations of the phenolic compounds in the white (fresh) garlic samples were observed at 24.15 mg/kg and it was found that caffeic and ferulic acids, epicatechin, apigenin and p-hydroxybenzoic acid were dominant. Resveratrol, which is present in trace amounts in fresh garlic, has shown a significant increase in black garlic. Allicin was found to be the predominant organosulfur compound in white garlic, whereas S-allyl-L-cysteine was dominant in black garlic. Antimicrobial activity and minimum inhibitory concentration of the garlic samples were evaluated on two test microorganisms (Staphylococcus auereus and Escherichia coli). The effects of the garlic extracts on cancer cell lines (A549, HuH-7, MCF-7, HCT-116) were also assessed. The anticancer effect of the black garlic extracts was observed at higher concentrations than the white garlic water extracts, but the white garlic and black garlic methanolic extracts were effective on all cancer cell lines within the concentration range used in the study.

Indexed as

GarlicPhytochemicalsPlant ExtractsAnti-Infective AgentsAntioxidantsCell Line, TumorDisulfidesEscherichia coliHumansMicrobial Sensitivity TestsPhenolsSulfinic AcidsTandem Mass SpectrometryallicinAnti-Infective AgentsAntioxidantsDisulfidesPhenolsPhytochemicalsPlant ExtractsSulfinic AcidsAllium sativum L; Black garlicAnticancer activityAntimicrobial activityBioactivityPhenolic profile

Identifiers

PMID40603873
PMCPMC12222484

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.