Evidence map›Paper›PMID 40603824›Full record

ArticleInterdisciplinary sciences, computational life sciences2026

Construction and Application of Traditional Chinese Medicine Knowledge Graph Based on Large Language Model.

Bo Zhang, Ruifang Li, Kedong Yin, Shuo Hua, Shiyu Li, Mengwan Jiang, Haoping An, Peng Li

Abstract read
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In one paragraph

Article in Interdisciplinary sciences, computational life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bo ZhangKey Laboratory of Functional Molecules for Biomedical Research, Henan University of Technology, Zhengzhou, 450001, P. R. China.
Ruifang LiKey Laboratory of Functional Molecules for Biomedical Research, Henan University of Technology, Zhengzhou, 450001, P. R. China. lrf@haut.edu.cn.ORCID http://orcid.org/0000-0002-4824-0930
Kedong YinKey Laboratory of Functional Molecules for Biomedical Research, Henan University of Technology, Zhengzhou, 450001, P. R. China.
Shuo HuaKey Laboratory of Functional Molecules for Biomedical Research, Henan University of Technology, Zhengzhou, 450001, P. R. China.
Shiyu LiKey Laboratory of Functional Molecules for Biomedical Research, Henan University of Technology, Zhengzhou, 450001, P. R. China.
Mengwan JiangSchool of Artificial Intelligence and Big Data, Henan University of Technology, Zhengzhou, 450001, P. R. China.
Haoping AnCollege of Information Science and Engineering, Henan University of Technology, Zhengzhou, 450001, P. R. China. hoaping@163.com.
Peng LiInstitute for Complexity Science, Henan University of Technology, Zhengzhou, 450001, P. R. China. lipeng@haut.edu.cn.

Funding

Open Project of the Institute of Complexity Science, Henan University of Technology CSKFJJ-2024-8
6 · The paper itself

Abstract

Traditional Chinese Medicine (TCM) is a vital component of the Chinese heritage, embodying a wealth of medical knowledge and distinctive therapeutic practices. A critical challenge in TCM modernization lies in extracting essential information from its complex and diverse knowledge system to develop knowledge-based services, which represents a cutting-edge research focus. This study proposes a Large Language Model (LLM)-driven approach for structuring TCM knowledge integrating historical TCM texts with open-source TCM datasets. A Fine-Tuning ChatGLM3-6B (FT-ChatGLM3) model was developed on the AliCloud DSW platform, optimized specifically for Chinese-language processing to enhance semantic understanding and knowledge extraction within TCM contexts. FT-ChatGLM3 powers an intelligent TCM Q&A system, significantly improving the accuracy and efficiency of diagnosis and therapeutic recommendations. Furthermore, a BERT-based TCM Entity Recognition (TCMER) model was developed, and a knowledge graph was constructed using FT-ChatGLM3's outputs. Experimental results demonstrate that FT-ChatGLM3 achieves strong performance in TCM applications, delivering precise diagnosis and treatment suggestions. The TCMER model also exhibits high efficacy, facilitating the systematization and structuring of TCM knowledge, while improving knowledge retrieval and consistency. The integration of FT-ChatGLM3 and TCMER not only accelerates the development of TCM knowledge graphs but also advances TCM modernization and its intelligent application in global healthcare.

Indexed as

KnowledgeLarge Language ModelsMedicine, Chinese TraditionalHumansFine-tuningFT-chatGLM3Knowledge graphLarge language model (LLM)Traditional chinese medicine (TCM)

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.