Evidence map›Paper›PMID 40603758›Full record

ReviewJournal of gastroenterology2025

Expert consensus on diagnostic guidelines for pediatric inflammatory bowel disease in Japan.

Takahiro Kudo, Katsuhiro Arai, Itaru Iwama, Shin-Ichiro Hagiwara, Takashi Ishige, Koji Yokoyama, Fumihiko Kakuta, Keisuke Jimbo, Hiroki Kondou, Yugo Takaki and 8 more

Abstract readReviewConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Takahiro KudoDepartment of Pediatrics, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan. t-kudo@juntendo.ac.jp.ORCID 0000-0003-4708-8049
Katsuhiro AraiDivision of Gastroenterology, Center for Pediatric Inflammatory Bowel Disease, National Center for Child Health and Development, Tokyo, Japan.
Itaru IwamaDivision of Gastroenterology and Hepatology, Saitama Children's Medical Center, Saitama, Japan.
Shin-Ichiro HagiwaraDepartment of Pediatric Gastroenterology, Nutrition and Endocrinology, Osaka Women's and Children's Hospital, Osaka, Japan.
Takashi IshigeDepartment of Pediatrics, Gunma University Graduate School of Medicine, Gunma, Japan.
Koji YokoyamaDepartment of Pediatrics, Jichi Medical University School of Medicine, Tochigi, Japan.
Fumihiko KakutaDepartment of Gastroenterology and Hepatology, Miyagi Children's Hospital, Sendai, Japan.
Keisuke JimboDepartment of Pediatrics, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Hiroki KondouDepartment of Pediatrics, Kindai University Nara Hospital, Nara, Japan.
Yugo TakakiDepartment of Pediatric Gastroenterology and Hepatology, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan.
Shingo KurasawaDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
Hiroki FujikawaDepartment of Pediatrics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Yuhki KoikeDepartment of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Mie, Japan.
Fumihito HiraiDepartment of Gastroenterology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Shinya AshizukaDepartment of Gastroenterology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Kenji WatanabeDepartment of Internal Medicine for Inflammatory Bowel Disease, University of Toyama, Toyama, Japan.
Toshiaki ShimizuDepartment of Pediatrics, Juntendo University Faculty of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Tadakazu HisamatsuDepartment of Gastroenterology and Hepatology, Kyorin University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel disease (IBD) can occur at any age. In pediatric patients, the disease may present with a broader range of symptoms and more severe course than in adults, due to ongoing growth and development. Therefore, pediatric IBD often exhibits an atypical clinical course and laboratory findings. It is essential to recognize differences in disease presentation, differential diagnoses, and evaluation strategies specific to children. The revised Porto criteria, proposed by the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) in 2014, are widely used globally, including in Japan, for the diagnosis of pediatric IBD. PURPOSE: Despite the widespread use of these criteria, no formal diagnostic guidelines for pediatric IBD have been developed in Japan. We aimed to support future guideline development by summarizing important diagnostic considerations and clinical practices for pediatric IBD in Japan.

methodsThis review was developed based on relevant international diagnostic guidelines and the expert opinions of Japanese pediatric gastroenterologists. It outlines key clinical and laboratory evaluations, as well as current treatment and follow-up approaches.

resultsWe summarized recommended diagnostic tests and clinical points that require special attention in children with suspected IBD. The article reflects both global standards and domestic clinical experience.

conclusionAlthough this article does not provide formal diagnostic criteria or assess evidence levels, it offers accurate and practical information to guide physicians and patients in the diagnosis and management of pediatric IBD in Japan.

Indexed as

Inflammatory Bowel DiseasesChildDiagnosis, DifferentialGastroenterologyHumansJapanChildrenCrohn’s diseaseInflammatory bowel diseasePediatricUlcerative colitis

Identifiers

PMID40603758
PMCPMC12378499

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.