Evidence map›Paper›PMID 40603753›Full record

ArticleIn vitro cellular & developmental biology. Animal2025

Overexpression of MEOX2 inhibits breast cancer cell metastasis by targeting oxidative stress-induced RGS5.

Yujun Tang, Jie Luo, Bin Jiang, Jian Deng, Jiehua Li, Liuqing Qin

Abstract read
PubMed Publisher
In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yujun TangDepartment of Plastic, The Second Affiliated Hospital of the University of South China, University of South China, Hengyang, 421001, China.
Jie LuoDepartment of Neurosurgery, The Second Affiliated Hospital of the University of South China, University of South China, Hengyang, 421001, China. 252333407@qq.com.
Bin JiangDepartment of Plastic, The Second Affiliated Hospital of the University of South China, University of South China, Hengyang, 421001, China.
Jian DengDepartment of Breast and Thyroid, The Second Affiliated Hospital of the University of South China, University of South China, Hengyang, 421001, China.
Jiehua LiDepartment of Gastrointestinal Glandular, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, 530021, China.
Liuqing QinDepartment of Gastrointestinal Glandular, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Nanning, 530021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the role of mesenchymal homeobox 2 (MEOX2) on breast cancer cell metastasis and its underlying mechanism. Overexpression of MEOX2 in human lymphatic endothelial cell (HLEC) lines was established to assess the adhesion and transendothelial migration of MCF7 and MDA-MB-231 cells to the HLEC cells. After being treated with the oxidative stress inducer H

Indexed as

Breast NeoplasmsHomeodomain ProteinsOxidative StressRGS ProteinsAnimalsCell AdhesionCell Line, TumorCell MovementCell ProliferationCell SurvivalEndothelial CellsFemaleGene Expression Regulation, NeoplasticHumansHydrogen PeroxideMCF-7 CellsHomeodomain ProteinsHydrogen PeroxideReactive Oxygen SpeciesRGS5 protein, humanRGS ProteinsBreast cancerMEOX2MetastasisOxidative stressRGS5

Identifiers

PMID40603753

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.