Evidence map›Paper›PMID 40603723›Full record

Articlenpj metabolic health and disease2025

mHealth low carbohydrate dietary intervention ameliorates glycaemic profile, blood pressure and weight status in people with type 2 diabetes.

Despina Kolivas, Liz Fraser, Ronald Schweitzer, Peter Brukner, George Moschonis

Abstract read
In one paragraph

Article in npj metabolic health and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Despina KolivasSchool of Allied Health, Human Services & Sport, La Trobe University, Bundoora, VIC, 3086, Australia. d.kolivas@latrobe.edu.au.ORCID http://orcid.org/0000-0003-1195-0688
Liz FraserWatson General Practice, 34 Windeyer Street, Watson, ACT, 2602, Australia.ORCID http://orcid.org/0009-0000-9108-2440
Ronald SchweitzerEast Bentleigh Medical Group, 873 Centre Road, Bentleigh East, VIC, 3165, Australia.ORCID http://orcid.org/0009-0005-2893-7967
Peter BruknerSchool of Allied Health, Human Services & Sport, La Trobe University, Bundoora, VIC, 3086, Australia.ORCID http://orcid.org/0000-0001-9923-4461
George MoschonisSchool of Allied Health, Human Services & Sport, La Trobe University, Bundoora, VIC, 3086, Australia. g.moschonis@latrobe.edu.au.ORCID http://orcid.org/0000-0003-3009-6675

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low carbohydrate diets (LCD) have shown efficacy in managing clinical outcomes in type 2 diabetes (T2D). Incorporating digital tools into health care provides an adjunct treatment modality, to educate patients and provide clinical support. This study examines the effect of a mobile health (mHealth) LCD application (app) on glycaemic profile, blood pressure and weight status, in people with T2D. The study is an online single-arm, pre-post study that recruited people with T2D from around Australia, referred via registered supporting general practitioners (GPs). The intervention (Defeat Diabetes app) provides education and resources on the use of a LCD for ongoing management of T2D. After 3 months, our cohort of 99 participants (mean age 59 ± 11 years, 55 females) showed reduced dietary carbohydrate intake as a proportion of overall energy (-14%kJ/day, 95% CI: -17 to -11). Improvement in the primary outcome HbA1c (-1.0%, 95% CI: -1.3 to -0.7), was associated with reduction in dietary carbohydrate intake. Systolic blood pressure (SBP) improved (-6 mmHg, 95% CI: -10 to -1), while 21 participants reduced their diabetes medication dose with two participants discontinuing all diabetes medication. These findings demonstrate that people with T2D receiving LCD education and resources through the Defeat Diabetes app for 3 months improved their glycaemic profile and SBP despite decreased overall medication usage in almost one third of the study sample prescribed medication at baseline.

Identifiers

PMID40603723
PMCPMC12118682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.