Evidence map›Paper›PMID 40603654›Full record

ReviewNpj imaging2024

Multimodal bioimaging across disciplines and scales: challenges, opportunities and breaking down barriers.

Johanna Bischof, Georgina Fletcher, Paul Verkade, Claudia Kuntner, Julia Fernandez-Rodriguez, Linda Chaabane, Leor Ariel Rose, Andreas Walter, Michiel Vandenbosch, Marc A M J van Zandvoort and 3 more

Abstract readReview
In one paragraph

Review in Npj imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
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  4. Tantalum-Based Nanomaterials: From Properties to Biomedical Applications.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
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  11. Convolutional-transformer fusion of ultrasound and diffuse optical tomography for breast lesion classification.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Johanna BischofEuro-BioImaging ERIC Bio-Hub, European Molecular Biology Laboratory (EMBL) Heidelberg, Meyerhofstraße 1, 69117, Heidelberg, Germany.
Georgina FletcherBioImagingUK and Royal Microscopical Society 37/38 St Clements Oxford, Oxford, OX4, 1AJ, UK.
Paul VerkadeSchool of Biochemistry, University of Bristol, Bristol, BS8 1TD, UK.
Claudia KuntnerDepartment of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.
Julia Fernandez-RodriguezCentre for Cellular Imaging, Sahlgrenska Academy, University of Gothenburg, SE-405 30, Gothenburg, Sweden.
Linda ChaabaneEuro-BioImaging ERIC Med-Hub, Institute of Biostructures and Bioimaging (IBB), Italian National Research Council (CNR), Via Nizza 52, Torino, 10126, Italy.
Leor Ariel RoseDepartment of Software and Information Systems Engineering, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Andreas WalterCenter of Optical Technologies, Aalen University, Aalen, Germany.
Michiel VandenboschDepartment FHML, Maastricht University, Maastricht Multimodal Molecular imaging institute, Maastricht, The Netherlands.
Marc A M J van ZandvoortDepartment of Genetics and Cell Biology, Maastricht University, Institutes CARIM, GROW, and MHeNS, Maastricht, the Netherlands.
Assaf ZaritskyDepartment of Software and Information Systems Engineering, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Antje KepplerEuro-BioImaging ERIC Bio-Hub, European Molecular Biology Laboratory (EMBL) Heidelberg, Meyerhofstraße 1, 69117, Heidelberg, Germany.
Maddy ParsonsRandall Centre for Cell and Molecular Biophysics, King's College London, Guy's Campus, London, SE1 1UL, UK. maddy.parsons@kcl.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/S018689/1Medical Research Council MR/W031469/1; MR/W024985/1Wellcome Trust
6 · The paper itself

Abstract

Multimodal bioimaging is a broad term used to describe experimental workflows that employ two or more different imaging modalities. Such approaches have been in use across life science domains for several years but these remain relatively limited in scope, in part due to the complexity of undertaking these types of analysis. Expanding these workflows to encompass diverse, emerging technology holds potential to revolutionize our understanding of spatial biology. In this perspective we reflect on the instrument and workflows in current use, emerging areas to consider and our experience of the barriers to broader adoption and progress. We propose several enabling solutions across the different challenge areas, emerging opportunities for consideration and highlight some of the key community activities to help move the field forward.

Identifiers

PMID40603654
PMCPMC12118647

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.