ArticleScientific reports2025
Bacterioruberin extract from Haloferax mediterranei induces apoptosis and cell cycle arrest in myeloid leukaemia cell lines.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Bacterioruberin fromInternational journal of molecular sciences · 2026Article
- Activatable Silicon-Xanthene Photosensitizer for Photodynamic Therapy of Glioblastoma.Pharmaceutics · 2026Article
- Looking at the fraction with Annexin V⁺ and propidium iodide⁺: insights into cell death types from preclinical studies in solid and haematological cancers.Apoptosis : an international journal on programmed cell death · 2026Review
- Recent Advances in Understanding Bio-Compounds from Haloarchaea.Journal of microbiology and biotechnology · 2026Review
- Characterization and Functional Evaluation of Carotenoids From Haloarcula rubripromontorii BS2.MicrobiologyOpen · 2026Article
- Microbial conversion of biodiesel waste for carotenoid production.Frontiers in bioengineering and biotechnology · 2026Article
- Bacterioruberin (CNutrients · 2025Review
- Carotenoids and Their Interaction with the Immune System.Antioxidants (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carotenoids, a diverse group of naturally occurring pigments, have gained attention for their potential anticancer properties. Among them, bacterioruberin (BR), a rare C50 carotenoid, has shown promising bioactivities. This study evaluates the antiproliferative and cytotoxic effects of a bacterioruberin-rich carotenoid extract (BRCE) derived from Haloferax (H.) mediterranei on myeloid leukaemia (ML) cell lines, including chronic myelogenous leukaemia (CML) and acute myelogenous leukaemia (AML) models. Using MTT assay, Annexin V/PI and AO/EtBr staining, CFDA-SE proliferation assay, PI-based cell cycle analysis, and H
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Registered trials
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