Evidence map›Paper›PMID 40603470›Full record

ArticleScientific reports2025

Chitosan elicitation enhances biomass and secondary metabolite production in Carlina acaulis L.

Maciej Strzemski, Sławomir Dresler, Barbara Hawrylak-Nowak, Przemysław Tkaczyk, Magdalena Kulinowska, Marcin Feldo, Filippo Maggi, Agnieszka Hanaka

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maciej StrzemskiDepartment of Analytical Chemistry, Medical University of Lublin, Chodźki 4a Street, 20-093, Lublin, Poland. maciejstrzemski@umlub.pl.ORCID http://orcid.org/0000-0002-0039-4455
Sławomir DreslerDepartment of Analytical Chemistry, Medical University of Lublin, Chodźki 4a Street, 20-093, Lublin, Poland.ORCID http://orcid.org/0000-0003-4413-3748
Barbara Hawrylak-NowakDepartment of Botany and Plant Physiology, Faculty of Environmental Biology, University of Life Sciences in Lublin, Akademicka 15 Street, 20-950, Lublin, Poland.ORCID http://orcid.org/0000-0002-2935-1491
Przemysław TkaczykDepartment of Agricultural and Environmental Chemistry, University of Life Sciences in Lublin, Akademicka 15 Street, 20-950, Lublin, Poland.ORCID http://orcid.org/0000-0001-7734-1872
Magdalena KulinowskaDepartment of Analytical Chemistry, Medical University of Lublin, Chodźki 4a Street, 20-093, Lublin, Poland.ORCID http://orcid.org/0000-0003-1374-7413
Marcin FeldoDepartment of Vascular Surgery, Medical University of Lublin, Staszica 11 St, 20-081, Lublin, Poland.ORCID http://orcid.org/0000-0001-7406-1728
Filippo MaggiChemistry Interdisciplinary Project (ChIP) Research Center, School of Pharmacy, University of Camerino, via Madonna delle Carceri, 62032, Camerino, Italy.ORCID http://orcid.org/0000-0003-1375-4744
Agnieszka HanakaDepartment of Plant Physiology and Biophysics, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Sklodowska University, Akademicka 19 Street, 20-033, Lublin, Poland. agnieszka.hanaka@mail.umcs.pl.ORCID http://orcid.org/0000-0002-0648-5681

Funding

Medical University of Lublin, Lublin, Poland DS 52
6 · The paper itself

Abstract

Carlina acaulis L. (Asteraceae) is a medicinal plant with a long history of use as an herbal remedy. Recently, this species attracted the interest of agrochemical companies due to the presence of valuable biopesticides among which the most promising is carlina oxide (COx). To stimulate the biosynthesis of its specialised metabolites by elicitation, a polysaccharide - chitosan was supplemented as chitosan lactate (ChL). The aim was to evaluate the effects of ChL soil and foliar application on the C. acaulis biomass, photosynthetic efficiency, and levels of the COx, chlorogenic acids, protocatechuic acid, schaftosides, and triterpenic acids. ChL has been shown to have no effect on shoot growth while considerably increasing root biomass. It improved photosynthetic efficiency and enhanced levels of specialised metabolites. Soil application of ChL significantly increased chlorogenic and neochlorogenic acid content in leaves, by approximately 330% and 70%, respectively compared to controls. In contrast, foliar application more strongly increased COx levels in roots (55% for foliar vs. 16% for soil treatment). This study has demonstrated that the application of ChL can be used as an inexpensive and accessible way to boost the production of valuable compounds in C. acaulis.

Indexed as

AsteraceaeBiomassChitosanSecondary MetabolismPhotosynthesisPlant LeavesPlant RootsSoilChitosanSoilCarlina oxideChlorogenic acidsElicitorsSchaftosidesSignaling moleculeTriterpenic acids

Identifiers

PMID40603470
PMCPMC12222969

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.