Evidence map›Paper›PMID 40603315›Full record

ArticleScientific reports2025

Time-dependent material properties and composition of the nonhuman primate uterine layers through gestation.

Daniella M Fodera, Echo Z Xu, Camilo A Duarte, Michelle H Wyss, Shuyang Fang, Xiaowei Chen, Michelle L Oyen, Joy Vink, Ivan Rosado-Mendez, Helen Feltovich and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Mechanical cues regulateMaterials today. Bio · 2026
    Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Daniella M FoderaDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Echo Z XuDepartment of Mechanical Engineering, Columbia University, New York, NY, USA.
Camilo A DuarteDepartment of Mechanical Engineering, Columbia University, New York, NY, USA.
Michelle H WyssDepartment of Biomedical Engineering, Virginia Tech, Blacksburg, VA, USA.
Shuyang FangDepartment of Mechanical Engineering, Columbia University, New York, NY, USA.
Xiaowei ChenDepartment of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
Michelle L OyenDepartment of Biomedical Engineering, Wayne State University, Detroit, MI, USA.
Joy VinkDepartment of Obstetrics & Gynecology, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Honolulu, HI, USA.
Ivan Rosado-MendezDepartment of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.
Helen FeltovichDepartment of Obstetrics & Gynecology, North Memorial Health System, Robbinsdale, MN, USA.
Timothy J HallDepartment of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA.
Kristin M MyersDepartment of Mechanical Engineering, Columbia University, New York, NY, USA. kmm2233@cumc.columbia.edu.

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Monitoring Changes in Cervical Microstructure During PregnancyR01HD072077 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI FELTOVICH, HELEN, HALL, TIMOTHY J · 2013 to 2022
$6.1M
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD072077National Science Foundation Graduate Research Fellowship Program DGE-2036197NICHD NIH HHS R01 HD072077NIH HHS P51 OD011106
6 · The paper itself

Abstract

The uterus is central to the establishment, maintenance, and delivery of a healthy pregnancy. Biomechanics is an important contributor to pregnancy success, and alterations to normal uterine biomechanical functions can contribute to an array of obstetric pathologies. Few studies have characterized the passive mechanical properties of the gravid human uterus, and ethical limitations have largely prevented the investigation of mid-gestation periods. To address this key knowledge gap, this study seeks to characterize the structural, compositional, and time-dependent micro-mechanical properties of the nonhuman primate (NHP) uterine layers in nonpregnancy and at three time-points in pregnancy: early 2

Indexed as

UterusAnimalsBiomechanical PhenomenaDeciduaEndometriumFemaleHumansMacaca mulattaMyometriumPregnancyMicroindentationPoro-viscoelasticityPregnancyReproductive biomechanicsRhesus macaqueUterus

Identifiers

PMID40603315
PMCPMC12223135

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.