ArticleBritish journal of haematology2025
Reproductive patterns and birth rates in acute leukaemia survivors: A Danish population-based cohort study.
Article in British journal of haematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Leukemia during pregnancy and survivorship: gestational age-stratified multidisciplinary management framework.Clinical and experimental medicine · 2026Review
- Reproductive patterns and birth rates in acute leukaemia survivors: A Danish population-based cohort study.British journal of haematology · 2025Article
- Back to life: Biological parenthood of young adult acute leukaemia survivors.British journal of haematology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Treatment-related infertility is of great concern to younger long-term survivors of acute leukaemia (AL). This study aimed to assess birth rates and cumulative incidences of first live birth, use of assisted reproduction technology (ART) and pregnancy outcomes in AL survivors compared to the Danish general population. Patients aged 18-45 years at AL diagnosis, alive and in remission 3 years after the date of diagnosis (index date), were included and matched 1:10 with leukaemia-free comparators on sex, age and parenthood status. A total of 401 AL survivors (183 females; 218 males) and 4010 matched comparators were followed for a median of 9.9 years. The median age at index was 37 years in females and 36 years in males. AL survivors had lower birth rates (incidence rate ratio: 0.77, 95% confidence interval: 0.61-0.99), lower 10-year cumulative incidences (females: 20.1% vs. 27.8%; males: 22.3% vs. 29.9%), a higher use of ART (females: 25.5% vs. 14.1%; males: 55.9% vs. 12.2%), but no higher degree of adverse pregnancy outcomes. This underscores the importance of informing patients of fertility-preservation options as well as of the risk of treatment-related infertility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.