Evidence map›Paper›PMID 40602798›Full record

Trial reportArquivos de neuro-psiquiatria2025

Supera cognitive stimulation study with cognitively-unimpaired older adults: methodology and initial results of a randomized controlled clinical trial.

Thais Bento Lima da Silva, Tiago Nascimento Ordonez, Gabriela Dos Santos, Laydiane Alves Costa, Ana Paula Bagli Moreira, Diana Dos Santos Bacelar, Maria Antonia Antunes de Souza, Sabrina Aparecida da Silva, Sonia Maria Dozzi Brucki, Monica Sanches Yassuda

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Arquivos de neuro-psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thais Bento Lima da SilvaUniversidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.ORCID 0000-0001-6034-0988
Tiago Nascimento OrdonezUniversidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.ORCID 0000-0003-0307-5895
Gabriela Dos SantosUniversidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.ORCID 0000-0002-1283-2731
Laydiane Alves CostaUniversidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.ORCID 0009-0004-9768-3860
Ana Paula Bagli MoreiraUniversidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.ORCID 0000-0003-3878-4907
Diana Dos Santos BacelarUniversidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.ORCID 0009-0007-6424-4361
Maria Antonia Antunes de SouzaUniversidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.ORCID 0009-0007-2813-4894
Sabrina Aparecida da SilvaUniversidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.ORCID 0009-0001-5388-3375
Sonia Maria Dozzi BruckiUniversidade de São Paulo, Faculdade de Medicina, Departamento de Neurologia, Divisão de Clínica Neurológica, Grupo de Neurologia Cognitiva e do Comportamento, São Paulo SP, Brazil.ORCID 0000-0002-8303-6732
Monica Sanches YassudaUniversidade de São Paulo, Escola de Artes, Ciências e Humanidades, Programa de Pós-Graduação em Gerontologia, São Paulo SP, Brazil.ORCID 0000-0002-9182-2450

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scientific investigations have highlighted the benefits of cognitive stimulation for cognitive, psychological, and social aspects in older individuals. However, there is a dearth of long-term, methodologically-rigorous studies. The aim of the present study was to describe the methods and the initial characteristics of the participants in a randomized controlled trial on cognitive stimulation. A total of 578 older individuals accepted invitations to participate in the study. Of these respondents, 362 met the eligibility criteria, and 255 were selected and randomized into the training, active control, and passive control groups. During the baseline stage (T0), 48 participants withdrew, resulting in a final T0 sample of 207 participants. The three groups were similar in terms of cognitive performance and sociodemographic and psychosocial variables, but they differed significantly regarding depressive symptoms, with the training group scoring higher. The methods herein described can help guide future research on cognitive stimulation in older adults.

Indexed as

CognitionCognitive Behavioral TherapyAgedAged, 80 and overDepressionFemaleHumansMaleMiddle AgedNeuropsychological TestsSocioeconomic FactorsTreatment Outcome

Identifiers

PMID40602798
PMCPMC12221690

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.