ArticleGenes to cells : devoted to molecular & cellular mechanisms2025
Effect of Retinal on Dictyostelium Cells During Development.
Article in Genes to cells : devoted to molecular & cellular mechanisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Effect of Retinal on Dictyostelium Cells During Development.Genes to cells : devoted to molecular & cellular mechanisms · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Retinal plays a key role in light absorption across prokaryotes and eukaryotes, both in rhodopsin and bacteriorhodopsin systems. The multicellular social amoeba Dictyostelium discoideum exhibits positive phototaxis. However, retinal binding proteins such as rhodopsin have not been found in the genome of Dictyostelium cells. Herein, we microscopically examined the effects of retinal on Dictyostelium cells. On adding all-trans-retinal to the medium, Dictyostelium cells retracted their pseudopodia and became rounded. This was unique to retinal among the tested vitamin A variants. Addition of all-trans-retinal at low concentrations did not cause cell rounding. However, it increased the frequency of cAMP signaling triggered during cell development. Results indicate that retinal acts on an unknown signaling pathway involving the cytoskeleton in Dictyostelium cells.
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Registered trials
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