Evidence map›Paper›PMID 40602370›Full record

ArticleThe American journal of tropical medicine and hygiene2025

Water Insecurity, Sociopolitical Instability, and Resurgence of Cholera in Haiti, 2022: An Outbreak Investigation.

Stanley Juin, Edwige Michel, Wilfredo R Matias, Evenel Thermidor, Molly F Franke, Michelle V Evans, Hetsner Denis, Yodeline Guillaume, Roberta Bouilly, Wisnel Mathurin and 9 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Stanley JuinCenter for Global Health, Massachusetts General Hospital, Boston, Massachusetts.
Edwige MichelDirection d'Épidémiologie des Laboratoires et de Recherche, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Wilfredo R MatiasCenter for Global Health Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts.
Evenel ThermidorDirection Nationale d'Eau Potable, Port-au-Prince, Haiti.
Molly F FrankeDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts.
Michelle V EvansDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts.
Hetsner DenisDirection d'Épidémiologie des Laboratoires et de Recherche, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Yodeline GuillaumeCenter for Global Health, Massachusetts General Hospital, Boston, Massachusetts.
Roberta BouillyDirection d'Épidémiologie des Laboratoires et de Recherche, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Wisnel MathurinDirection d'Épidémiologie des Laboratoires et de Recherche, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Katilla PierreDirection d'Épidémiologie des Laboratoires et de Recherche, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Valusnor CompereLaboratoire National de Santé Publique, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Kenold RendelDirection d'Épidémiologie des Laboratoires et de Recherche, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Hebrelienne AmelusDirection d'Épidémiologie des Laboratoires et de Recherche, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Lesly AndrecyDirection d'Épidémiologie des Laboratoires et de Recherche, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Gerard A JosephLaboratoire National de Santé Publique, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Jacques BoncyLaboratoire National de Santé Publique, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Donald LafontantDirection d'Épidémiologie des Laboratoires et de Recherche, Ministère de la Santé Publique et de la Population, Port-au-Prince, Haiti.
Louise C IversCenter for Global Health, Massachusetts General Hospital, Boston, Massachusetts.

Funding

PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
Immune Responses to Vibrio cholerae infection and vaccination in HaitiR01AI099243 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HARRIS, JASON B, IVERS, LOUISE C. · 2012 to 2022
$7.9M
NIAID NIH HHS R01 AI099243NIAID NIH HHS T32 AI007433
6 · The paper itself

Abstract

We investigated a resurgence of cholera in Haiti in 2022, occurring after 3 years without cases. We analyzed data from the National Cholera Surveillance System for the first reported cases in 2022 and interviewed field epidemiology teams. We used logistic regression to identify risk factors associated with confirmed cholera. Few suspected cases reported ever receiving oral cholera vaccine (14%) or previous hospitalization for cholera (7%). Recently changing water sources were associated with culture-confirmed cholera (odds ratio 5.55, 95% CI 2.13-15.12). Spatial analysis of cholera cases revealed significant clustering (P = 0.001) and low prevalence (11%, 15 of 136) of residual chlorine in private water points in the affected area. Qualitative analysis suggested a link between cholera resurgence and an acute lack of access to safe water because of gang violence. Ongoing response to cholera in Haiti is crucial, alongside sustained investment in long-term solutions like improved water and sanitation infrastructure and addressing socioeconomic issues.

Indexed as

CholeraDisease OutbreaksWater InsecurityWater SupplyAdolescentAdultChildChild, PreschoolCholera VaccinesFemaleHaitiHumansMaleMiddle AgedRisk FactorsSanitationCholera Vaccines

Identifiers

PMID40602370
PMCPMC12410162

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.