Evidence map›Paper›PMID 40602027›Full record

ArticleJournal of psychiatric research2025

The prevalence of moral distress and moral injury among U.S. veterans.

Brett T Litz, Hannah E Walker, Robert H Pietrzak, Luke Rusowicz-Orazem

Abstract read
In one paragraph

Article in Journal of psychiatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brett T LitzVA Boston Healthcare System, 2 Avenue de Lafayette, Boston, MA, 02111, United States; Boston University and Boston University School of Medicine, 881 Commonwealth Avenue, Boston, MA, 02215, United States; Boston University and Boston University School of Medicine, 715 Albany Street. E-113, Boston, MA, 02118, United States. Electronic address: litzb@bu.edu.
Hannah E WalkerVA Boston Healthcare System, 2 Avenue de Lafayette, Boston, MA, 02111, United States. Electronic address: Hannah.Walker@va.gov.
Robert H PietrzakNational Center for PTSD, VA Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT, 06516, United States; Yale School of Medicine, 301 Cedar Street, New Haven, CT, 06519, United States. Electronic address: rhpietrzak@gmail.com.
Luke Rusowicz-OrazemBoston University School of Public Health, Talbot Building, C202, 715 Albany Street, Boston, MA, 02118, United States. Electronic address: lukejro@bu.edu.

Funding

RRD VA I01 RX003915
6 · The paper itself

Abstract

Moral injury is a syndrome that involves adverse outcomes stemming from experiences violating deeply held moral beliefs. Moral injury has emerged as a distinct mental health concern, yet its prevalence among U.S. veterans remains uncertain. The aim of this study was to determine the prevalence of potentially morally injurious events (PMIEs), moral distress, and moral injury among U.S. veterans. This cross-sectional study surveyed a nationally representative sample of 3002 U.S. veterans using KnowledgePanel. The Moral Injury Outcome Scale assessed PMIE exposure, moral distress (subclinical), moral injury (clinical syndrome), and their functional impact. Among respondents, 44.7 % (95 % CI, 42.1-47.2) endorsed PMIEs; 45.2 % reported witnessing inhumanity, 40.2 % were directly affected by others' transgressions, and 14.0 % reported perpetrating transgressive acts. The weighted prevalence of moral distress and moral injury among PMIE endorsers was 9.1 % (95 % CI, 7.1-11.2) and 13.1 % (95 % CI, 9.9-16.3), respectively. In the full sample, prevalence was 4.1 % (95 % CI, 3.1-5.0) for moral distress and 5.9 % (95 % CI, 4.4-7.4) for moral injury. Moral injury was associated with significant functional impairment, with most cases characterized by shame-related (47.8 %) or blended subvariant symptoms (33.3 %). Approximately 664,000 and 955,000 U.S. veterans report functionally impairing moral distress and moral injury, respectively. These findings highlight the need for surveillance, mitigation, and treatment for these unique mental health challenges.

Indexed as

MoralsPsychological DistressVeteransAdultAgedCross-Sectional StudiesEthical DilemmasFemaleHumansMaleMiddle AgedPrevalenceUnited StatesYoung AdultMoral distressMoral injuryMoral injury outcome scalePotentially morally injurious eventsVeterans

Identifiers

PMID40602027
PMCPMC12915357

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.