Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
16 authors.
Zhe DongNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-7366-8939
Yu FengNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-9068-3746
Keziah DiegoNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Austin M BaggettaNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0003-0852-1807
Brian M SweisNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-2123-5824
Zachary T PenningtonNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-9423-9319
Sophia I LamsiferNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0009-0004-3087-2659
Yosif ZakiNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-8167-0182
Federico SangiulianoDepartment of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Paul A PhilipsbergNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-9332-0342
Denisse Morales-RodriguezNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-3272-7023
Daniel KircherNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-5710-1123
Paul SlesingerNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-3868-7528
Tristan ShumanNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0003-2310-6142
Daniel AharoniDepartment of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0003-4931-8514
Denise J CaiNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-7729-0523
Funding
Pasinetti: Project 3; Role of Microbiome in Promotion of Cognitive and Psychological Resilience (Faith)P50AT008661 · NCCIH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WANG, JUN · 2015 to 2019
$11.2M
Using neuroeconomics to disentangle the transcriptional mechanisms underlying resilience versus susceptibility to stressR01MH051399 · NIMH · YALE UNIVERSITY · PI NESTLER, ERIC J. · 1994 to 2023
$10.2M
Circuit Mechanisms of Retrospective Memory-LinkingR01MH120162 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Denise Jade Cai · 2020 to 2026
$3.9M
Circuits Driving Spatial Coding Deficits in EpilepsyR01NS116357 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SHUMAN, TRISTAN · 2021 to 2025
$2.8M
Building and sharing next generation open-source, wireless, multichannel miniaturized microsopes for imaging activity in freely behaving miceU01NS094286 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GOLSHANI, PEYMAN, KHAKH, BALJIT · 2015 to 2017
$2.7M
How does the brain maximize storage capacity?DP2MH122399 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CAI, DENISE JADE · 2019 to 2020
$2.6M
Research Network on Animal Models to Understand Social Dimensions of AgingR24AG065172 · NIA · UNIVERSITY OF MINNESOTA · PI Susan C. Alberts, Alessandro Bartolomucci · 2020 to 2026
$2.6M
Neuroeconomic mechanisms of counterfactual thinkingR01MH136230 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Brian Musa Sweis · 2024 to 2026
$2.4M
Development of new photo-releasable neuropeptide nano-vesicles for studying modulation in the brainRF1NS110499 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI QIN, ZHENPENG, SLESINGER, PAUL A · 2019 to 2019
$2.4M
Entorhinal-hippocampal interactions during progressive memory impairments in mouse models of Alzheimer's disease pathologyRF1AG072497 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SHUMAN, TRISTAN · 2022 to 2024
$2.4M
Closed-loop Control of Interneuron Spike Timing in EpilepsyR01NS136590 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Tristan Shuman · 2024 to 2026
$1.8M
Entorhinal-hippocampal interactions during progressive memory impairments in mouse models of Alzheimer's disease pathologyR01AG072497 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Tristan Shuman · 2025 to 2026
Miniaturized fluorescence microscopes (miniscopes) enable imaging of calcium events from a large population of neurons in freely behaving animals. Traditionally, miniscopes have only been able to record from a single fluorescence wavelength. Here, we present an open-source dual-channel miniscope that simultaneously records two wavelengths in freely behaving animals. To enable simultaneous acquisition of two fluorescent wavelengths, we incorporated two CMOS sensors into a single miniscope. To validate our dual-channel miniscope, we imaged hippocampal CA1 region that co-expressed a dynamic calcium indicator (GCaMP) and a static nuclear signal (dTomato) while mice ran on a linear track. Our results suggest that, even when neurons were registered across days using dTomato signals, hippocampal spatial coding changes over time. In conclusion, our dual-channel miniscope enables imaging of two fluorescence wavelengths with minimal cross-talk between the two channels, opening the doors to a multitude of previously inaccessible experimental possibilities.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Simultaneous two-color imaging with a dual-channel miniscope in freely behaving mice. · full record | OpenQuestion